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Waldenström macroglobulinemia 

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  1. 13-08-2018 | Waldenström macroglobulinemia | News | Article

    Ibrutinib monotherapy promising for untreated Waldenström macroglobulinemia

    Phase II trial results suggest that the Bruton tyrosine kinase inhibitor ibrutinib has high activity and is well tolerated in symptomatic, treatment-naïve patients with Waldenström macroglobulinemia.

  2. 03-06-2018 | B-cell lymphoma | ASCO 2018 | Article
    News in brief

    Ibrutinib, rituximab duo boosts Waldenström macroglobulinemia outcomes

    Treatment with the combination of ibrutinib and rituximab results in better outcomes for patients with newly diagnosed or recurrent Waldenström macroglobulinemia than rituximab alone, phase III trial findings indicate.

  3. 31-05-2018 | B-cell lymphoma | Article

    Phase 3 Trial of Ibrutinib plus Rituximab in Waldenström’s Macroglobulinemia

    Dimopoulos MA et al.  N Engl J Med  2018; 378(25): 2399-2410. doi:10.1056/NEJMoa1802917

  4. 01-08-2016 | Lymphoma | Article

    Diagnostic and predictive biomarkers for lymphoma diagnosis and treatment in the era of precision medicine

    Its inhibitor, ibrutinib, shows promising efficacy in patients with relapsed/refractory chronic lymphocytic leukemia/small lymohocytic lymphoma, mantle lymphoma, follicular lymphoma, activated B-cell-like diffuse large B-cell lymphoma, lymphoplasmacytic lymphoma/Waldenstrom macroglobulinemia, primary diffuse large B-cell lymphoma of the central nervous system, and marginal zone lymphomas which also have aberrant Btk activity. 159, 160 Figure 5.

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