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Breast cancer

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a premier resource for the latest clinical information in medicine.

Expert opinion

Breast cancer-related lymphedema management: Current state and future directions

Lymphedema management

Breast cancer-related lymphedema is a debilitating complication of breast cancer surgery. Babak Mehrara (Memorial Sloan Kettering Cancer Center, NY, USA) outlines the current state of lymphedema management and poses some questions for the future.

medwireNews@ASCO2018

Ovarian suppression enhances outcome in premenopausal breast cancer

Adding ovarian suppression to tamoxifen significantly improves disease-free survival over tamoxifen alone in premenopausal women with hormone receptor-positive breast cancer, the latest data from the SOFT and TEXT trials show.

medwireNews@ASCO2018

Gene assay could help women with early breast cancer avoid chemotherapy

Gene assay

Women with hormone receptor-positive, HER2-negative, axillary node-negative breast cancer who have a midrange score on the 21-tumor gene assay may be spared adjuvant chemotherapy, phase III study data show.

Expert opinion

Challenges of an aging and increasingly obese breast cancer survivor population: Are we ready?

Obesity and breast cancer

In an aging population with rising obesity levels, comorbidities and worse overall prognoses for breast cancer patients are a growing concern. Damien Hansra (Cancer Treatment Centers of America, GA, USA) calls for more education and preparation to combat this concerning public health threat.

Expert opinion

New paradigm: Testing elimination of breast cancer surgery after neoadjuvant systemic therapy

Figure 1

Neoadjuvant chemotherapy can be so effective at shrinking breast tumors in some patients that it has raised the possibility of avoiding surgery altogether. Henry Kuerer (MD Anderson, USA) discusses the exciting recent advances in this area.

10-07-2018 | Breast cancer | News

Acupuncture benefits unclear for aromatase inhibitor–related athralgia

Acupuncture may provide modest reductions in aromatase inhibitor-related joint pain in postmenopausal women with early-stage breast cancer, results of a multicenter study suggest.

28-06-2018 | Surgery | Editorial | Article

Breast cancer-related lymphedema management: Current state and future directions

Breast cancer-related lymphedema is a debilitating complication of breast cancer surgery. Babak Mehrara (Memorial Sloan Kettering Cancer Center, NY, USA) outlines the current state of lymphedema management and poses some questions for the future.

27-06-2018 | Breast cancer | News

Higher BMI linked to reduced premenopausal breast cancer risk

Increased adiposity is associated with a decreased risk for developing breast cancer before menopause, confirms a pooled analysis published in JAMA Oncology.

Themed collections

30-05-2018 | Breast cancer | Themed collection | Collection

Best of JCO™ 2017: Breast Cancer Edition

The content compiled here represents some of the most-accessed original research from recently published Journal of Clinical Oncology articles across a range of topics including hormone receptor positive breast cancer, triple-negative breast cancer and molecular imaging.

11-04-2018 | Liquid biopsy | Themed collection | Collection

Liquid biopsy in oncology

This themed content collection highlights the role of liquid biopsy in the management of patients with solid tumors and evaluates the role of liquid biopsy in different types of cancer.

14-08-2017 | Breast cancer | Themed collection | Collection

Heterogeneity of triple-negative breast cancer: Implications for therapy

This themed content collection focuses on recent advances in our understanding of the molecular and biological features of triple negative breast cancer and potential therapeutic strategies and novel approaches to targeted therapy.

Journal articles and book chapters

27-06-2018 | Targeted therapy | Article

Selection of Optimal Adjuvant Chemotherapy and Targeted Therapy for Early Breast Cancer: ASCO Clinical Practice Guideline Focused Update

Denduluri N et al. J Clin Oncol 2018; JCO2018788604. doi:10.1200/JCO.2018.78.8604

04-06-2018 | Breast cancer | Article

BRCA1/2 testing: therapeutic implications for breast cancer management

Tung NM, Garber JE. Br J Cancer 2018. doi:10.1038/s41416-018-0127-5

04-06-2018 | Cancer immunotherapy | Article

Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer

Zacharakis N et al. Nat Med 2018; 24: 724–730. doi:10.1038/s41591-018-0040-8

04-06-2018 | Breast cancer | Article

Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer

Francis PA et al. N Engl J Med 2018. doi:10.1056/NEJMoa1803164

Images and illustrations

12-04-2018 | Breast cancer | Images and illustration slides | Collection

Breast mammography

This downloadable powerpoint slide set comprises a collection of high quality images that depict the use of mammography in breast cancer screening and diagnosis. These slides can be used for reference purposes or for inclusion in one’s own slide sets. Slide notes are included where appropriate. Source:Bassett LW et al. Breast Imaging. In: Jatoi I, Kaufmann M, eds. Management of Breast Diseases. Springer Berlin Heidelberg.

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