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Squamous cell carcinoma 

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  1. 10-08-2022 | Cutaneous squamous cell carcinoma | Adis Journal Club | Article
    Advances in Therapy

    Identification of Metastasis-Associated Genes in Cutaneous Squamous Cell Carcinoma Based on Bioinformatics Analysis and Experimental Validation

    DOI [Teaser] Key Summary Points Nineteen hub genes related to cutaneous squamous cell carcinoma (cSCC) metastasis have been identified in GSE98767 data set of cSCC.

  2. 28-01-2022 | Basal cell carcinoma | Adis Journal Club | Article
    Advances in Therapy

    New Emerging Treatment Options for Advanced Basal Cell Carcinoma and Squamous Cell Carcinoma

    Objective of this review is to analyze and discuss the novel therapies for advanced basal cell carcinoma and squamous cell carcinoma to obtain a sharper perspective of the available treatment options.

  3. 07-01-2022 | Cutaneous squamous cell carcinoma | Adis Journal Club | Article
    Dermatology and Therapy

    Current Methods and Caveats to Risk Factor Assessment in Cutaneous Squamous Cell Carcinoma (cSCC): A Narrative Review

    Arron Abstract Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer, and the number of deaths due to cSCC is estimated to be greater than the number attributed to melanoma.

  4. 02-10-2018 | FDA | News | Article
    approvalsWatch

    First advanced cutaneous squamous cell carcinoma drug approved

    medwireNews : The US FDA has approved use of the PD-1 inhibitor cemiplimab-rwlc for the treatment of patients with metastatic cutaneous squamous cell carcinoma (CSCC) or locally advanced disease who are unable to undergo surgery or radiotherapy with curative intent.

  5. 04-06-2018 | Cutaneous squamous cell carcinoma | Article

    PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma

    Migden MR et al.  N Engl J Med  2018. doi:10.1056/NEJMoa1805131

  6. 26-03-2018 | Cutaneous squamous cell carcinoma | Article

    Erlotinib in the treatment of recurrent or metastatic cutaneous squamous cell carcinoma: A single-arm phase 2 clinical trial

    Gold KA et al. Cancer  2018; 124(10): 2169-2173. doi:10.1002/cncr.31346

  7. 05-02-2016 | Non-melanoma skin cancer | Article

    Basal cell carcinoma, squamous cell carcinoma and melanoma of the head and face

    Feller L. et al. Head Face Med 2016; 12: 11. doi:10.1186/s13005-016-0106-0

  8. 30-04-2016 | Non-melanoma skin cancer | Article

    Epidemiology and outcomes of cutaneous squamous cell carcinoma

    Karia PS. In: High-risk cutaneous squamous cell carcinoma . Edited by Schmults CD. Springer-Verlag Berlin Heidelberg, 2016. doi:10.1007/978-3-662-47081-7_9

  9. 27-07-2017 | Head and neck cancers | Article

    Prognostic implications of human papillomavirus status for patients with non-oropharyngeal head and neck squamous cell carcinomas

    This retrospective, observational, large cohort study compares overall survival of patients with human papilloma virus-positive and negative non-oropharyngeal head and neck squamous cell carcinomas. Ko HC, Harari PM, Sacotte RM et al. J Cancer Res Clin Oncol 2017. doi:10.1007/s00432-017-2481-8

  10. 04-06-2016 | Non-melanoma skin cancer | Article

    Management of high-risk squamous cell carcinoma of the skin

    Fu T, Aasi SZ, & Hollmig ST. Curr Treat Options in Oncol 2016; 17: 34. doi:10.1007/s11864-016-0408-2

  11. 30-04-2016 | Non-melanoma skin cancer | Article

    Management of widely metastatic and unresectable cutaneous squamous cell carcinoma

    Hanna GL et al. In: High-risk cutaneous squamous cell carcinoma . Edited by Schmults CD.  Springer-Verlag Berlin Heidelberg, 2016. doi:10.1007/978-3-662-47081-7_9

  12. 01-03-2016 | Head and neck cancers | Book chapter | Article

    Emerging molecular targets in the treatment of head and neck squamous cell carcinoma

    This chapter describes emerging molecular targets for the treatment of head and neck squamous cell carcinoma, supporting preclinical evidence, and published and ongoing clinical trials. Warner BM & Grandis J. In:  Targeting Oral Cancer . Edited by Fribley AM. Springer International Publishing, 2016. doi:10.1007/978-3-319-27647-2_8

  13. 16-09-2014 | Esophageal cancer | Book chapter | Article

    Pathology of esophageal squamous cell carcinoma

    In this chapter, Nakanishi explores the macroscopic and microscopic features of esophageal squamous cell carcinoma specimens and summarizes the various subtypes of the disease. Nakanishi Y. In: Esophageal Squamous Cell Carcinoma . Edited by Ando N. Springer Japan, 2015. doi:10.1007/978-4-431-54977-2_2

  14. 04-08-2015 | Non-melanoma skin cancer | Article

    Staging and management of high-risk cutaneous squamous cell carcinoma

    This review article  provides  an up-to-date information on the traditional and alternative staging systems for cutaneous squamous cell carcinoma (CSCC) and the identification and management of patients with high-risk CSCC. Karia PS, Ruiz ES, Schmults CD. Curr Derm Rep 2015;4:168. doi:10.1007/s13671-015-0115-4

  15. 11-03-2016 | Head and neck cancers | Article

    Pretreatment oral hygiene habits and survival of head and neck squamous cell carcinoma (HNSCC) patients

    This interview-based study demonstrates that annual dental visits, daily teeth cleaning and use of floss are associated with longer overall survival in patients with head and neck squamous cell carcinoma. Friemel J et al. BMC Oral Health 2016; 16: 33. doi:10.1186/s12903-016-0185-0

  16. 12-09-2017 | Treatment | Article

    A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer

    Reynolds KL, Bedard PL, Lee SH et al. BMC Cancer 2017; 17:646. doi:10.1186/s12885-017-3641-6

  17. 22-09-2023 | KRAS inhibitors | News | Article

    Novel KRAS inhibitor elicits ‘durable responses’ in KRAS G12C mutation-positive tumors

    This included three patients with pancreatic adenocarcinoma and one patient each with anal adenocarcinoma, cholangiocarcinoma, endometrial squamous-cell carcinoma, large-cell neuroendocrine carcinoma of the lung, and stomach adenocarcinoma.

  18. 25-05-2023 | Checkpoint blockade | News | Article

    Real-world data provide reassurance for ICI use in people with HIV and cancer

    The most common tumor type in the cohort was non-small-cell lung cancer (NSCLC), in 28%, followed by hepatocellular carcinoma (HCC) and head and neck squamous cell carcinoma (HNSCC), in a respective 11% and 10% of participants.

  19. 13-07-2022 | Immunotherapy | News | Article

    ICI therapy feasible in advanced cancer patients with kidney transplant using immunosuppression

    Their phase 1 study included 17 patients with incurable, locally advanced or metastatic tumors, namely cutaneous cell carcinoma (35%) or squamous cell carcinoma (18%) of the head and neck, cancers of the kidney (12%), liver (6%), lung (6%), or colon (6%), Merkel cell carcinoma (12%), or melanoma (6%) from three Australian hospitals.

  20. 11-04-2022 | ALK-mutated NSCLC | Interview | Article

    Pathologic testing for ALK and ROS1 aberrations in NSCLC

    What is for sure is that ALK and ROS1 rearrangement are very infrequent in squamous cell carcinoma.

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