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19 search results for:

Cutaneous squamous cell carcinoma 

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  1. 10-08-2022 | Cutaneous squamous cell carcinoma | Adis Journal Club | Article
    Advances in Therapy

    Identification of Metastasis-Associated Genes in Cutaneous Squamous Cell Carcinoma Based on Bioinformatics Analysis and Experimental Validation

    DOI [Teaser] Key Summary Points Nineteen hub genes related to cutaneous squamous cell carcinoma (cSCC) metastasis have been identified in GSE98767 data set of cSCC.

  2. 07-01-2022 | Cutaneous squamous cell carcinoma | Adis Journal Club | Article
    Dermatology and Therapy

    Current Methods and Caveats to Risk Factor Assessment in Cutaneous Squamous Cell Carcinoma (cSCC): A Narrative Review

    Arron Abstract Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer, and the number of deaths due to cSCC is estimated to be greater than the number attributed to melanoma.

  3. 02-10-2018 | FDA | News | Article
    approvalsWatch

    First advanced cutaneous squamous cell carcinoma drug approved

    medwireNews : The US FDA has approved use of the PD-1 inhibitor cemiplimab-rwlc for the treatment of patients with metastatic cutaneous squamous cell carcinoma (CSCC) or locally advanced disease who are unable to undergo surgery or radiotherapy with curative intent.

  4. 04-06-2018 | Cutaneous squamous cell carcinoma | Article

    PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma

    Migden MR et al.  N Engl J Med  2018. doi:10.1056/NEJMoa1805131

  5. 26-03-2018 | Cutaneous squamous cell carcinoma | Article

    Erlotinib in the treatment of recurrent or metastatic cutaneous squamous cell carcinoma: A single-arm phase 2 clinical trial

    Gold KA et al. Cancer  2018; 124(10): 2169-2173. doi:10.1002/cncr.31346

  6. 30-04-2016 | Non-melanoma skin cancer | Article

    Epidemiology and outcomes of cutaneous squamous cell carcinoma

    Karia PS. In: High-risk cutaneous squamous cell carcinoma . Edited by Schmults CD. Springer-Verlag Berlin Heidelberg, 2016. doi:10.1007/978-3-662-47081-7_9

  7. 30-04-2016 | Non-melanoma skin cancer | Article

    Management of widely metastatic and unresectable cutaneous squamous cell carcinoma

    Hanna GL et al. In: High-risk cutaneous squamous cell carcinoma . Edited by Schmults CD.  Springer-Verlag Berlin Heidelberg, 2016. doi:10.1007/978-3-662-47081-7_9

  8. 04-08-2015 | Non-melanoma skin cancer | Article

    Staging and management of high-risk cutaneous squamous cell carcinoma

    This review article  provides  an up-to-date information on the traditional and alternative staging systems for cutaneous squamous cell carcinoma (CSCC) and the identification and management of patients with high-risk CSCC. Karia PS, Ruiz ES, Schmults CD. Curr Derm Rep 2015;4:168. doi:10.1007/s13671-015-0115-4

  9. 13-07-2022 | Immunotherapy | News | Article

    ICI therapy feasible in advanced cancer patients with kidney transplant using immunosuppression

    Their phase 1 study included 17 patients with incurable, locally advanced or metastatic tumors, namely cutaneous cell carcinoma (35%) or squamous cell carcinoma (18%) of the head and neck, cancers of the kidney (12%), liver (6%), lung (6%), or colon (6%), Merkel cell carcinoma (12%), or melanoma (6%) from three Australian hospitals.

  10. 28-01-2022 | Basal cell carcinoma | Adis Journal Club | Article
    Advances in Therapy

    New Emerging Treatment Options for Advanced Basal Cell Carcinoma and Squamous Cell Carcinoma

    Cutaneous squamous cell carcinoma is the second most frequent malignant skin cancer; when presenting in advanced or metastatic stage, alternative treatments are required; cemiplimab is a human monoclonal antibody directed against programmed cell death-1 receptor that acts by blocking T-cell inactivation and is the first drug approved for the treatment of adult patients with metastatic or locally advanced cutaneous squamous cell carcinoma.

  11. 15-10-2021 | Treatment | Adis Journal Club | Article
    Advances in Therapy

    Non-Surgical Treatments for Keratinocyte Carcinomas

    In recent decades, the incidence of keratinocyte carcinomas, which include basal cell carcinoma and cutaneous squamous cell carcinoma, has been steadily increasing globally (Rogers et al. in JAMA Dermatol 151(10):1081–1086. 

  12. 27-03-2018 | Head and neck cancers | News | Article

    No benefit of adding chemotherapy to postop radiation in cutaneous SCCHN

    Phase III trial findings suggest that the addition of concomitant chemotherapy to postoperative radiotherapy does not improve the outcomes of patients with high-risk cutaneous squamous cell carcinoma of the head and neck.

  13. 05-01-2018 | Non-melanoma skin cancer | News | Article

    Topical fluorouracil may have role in cutaneous SCC chemoprevention

    A single course of topical fluorouracil can prevent the occurrence of cutaneous squamous cell carcinoma requiring surgery in the first year after use, trial results suggest.

  14. 30-04-2016 | Non-melanoma skin cancer | Article

    Tumor staging systems and prognostic stratification

    Jambusaria-Pahlajani A. In:  High-risk cutaneous squamous cell carcinoma . Edited by Schmults CD. Springer-Verlag Berlin Heidelberg, 2016. doi:10.1007/978-3-662-47081-7_2

  15. 11-11-2016 | Treatment | Article

    Combinatorial immunotherapy for melanoma

    Objective clinical responses were seen in 5 of 11 (45%) patients in the melanoma group and 4 of 6 (66%) patients in the synovial cell carcinoma group.

  16. 11-03-2017 | Non-melanoma skin cancer | Article

    Nonmelanoma skin cancer and risk of all-cause and cancer-related mortality: a systematic review

    Barton V et al. Arch Dermatol Res 2017; 309: 243–251. doi:10.1007/s00403-017-1724-5

  17. 04-06-2016 | Non-melanoma skin cancer | Article

    Management of high-risk squamous cell carcinoma of the skin

    Fu T, Aasi SZ, & Hollmig ST. Curr Treat Options in Oncol 2016; 17: 34. doi:10.1007/s11864-016-0408-2

  18. 05-02-2016 | Non-melanoma skin cancer | Article

    Basal cell carcinoma, squamous cell carcinoma and melanoma of the head and face

    Feller L. et al. Head Face Med 2016; 12: 11. doi:10.1186/s13005-016-0106-0

  19. 24-07-2015 | Treatment | Article

    Evolving synergistic combinations of targeted immunotherapies to combat cancer

    On the basis of these extremely encouraging efficacy results, the combination of ipilimumab and nivolumab has been or is being explored in Phase III studies in renal cell carcinoma and NSCLC 110, 111 , and earlier-phase clinical trials are being conducted in various other tumour types (small-cell lung, triple-negative breast, pancreatic, gastric and bladder cancer).

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