Marije Hamaker (Diakonessenhuis Utrecht, the Netherlands) and Siri Rostoft (University of Oslo, Norway) say in a related commentary that the study “represents a leap forward in geriatric oncology.”

DOI [Teaser] Key Points for Decision Makers The dominant approaches to modeling the cost effectiveness of immuno-oncology (IO) therapies in advanced non-small cell lung cancer are Markov and partitioned survival models.

Medical oncology healthcare professionals often have conflicting opinions regarding the clinical effectiveness, patient experience, access to care, and financial impact of using telehealth video consultations, US research shows.

Researchers report a marked decrease in the number of oncology clinical trials launched during the COVID-19 pandemic compared with the prepandemic period.

There's a new home for news and congress coverage! Catch up on all the top stories and latest evidence in oncology research with our ESMO congress hub page.  Learn more »

The primary endpoint of biochemical response as well as the secondary endpoints of complete biochemical response and progression-free survival (PFS) were significantly improved with the use of SBRT, reports the research team in the Journal of Clinical Oncology .

The approach “reduced thromboembolism with a desirable number needed to treat, without safety concerns, and with reduced mortality,” say Marliese Alexander (Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia) and team in JAMA Oncology .

Erin Schenk highlights some of the lung cancer immuno-oncology studies that you may have missed at the virtual 2020 ASCO Annual Meeting (8:23).

This benefit “occurred without exacerbating the toxicities associated with systemic therapies,” note Ticiana Leal (Winship Cancer Institute at Emory University, Atlanta, Georgia, USA) and co-investigators in The Lancet Oncology .

By contrast, there was no such association for the development of arterial thromboembolism (ATE), but the risk for death following VTE or ATE was higher, albeit not statistically significantly, for patients with recent exposure to anticancer treatment, note the researchers in JAMA Oncology .

“The clinical safety analysis concludes that the AI-supported screen-reading procedure can be considered safe,” report Kristina Lång, from Lund University in Malmö, Sweden, and co-authors in The Lancet Oncology .

As reported in The Lancet Oncology , the phase 2 study enrolled 158 patients who had not received prior systemic treatment for stage IV non-clear-cell RCC.

The researchers say in the Journal of Clinical Oncology that these are “the first prospective data for a KRAS G12C inhibitor” in this patient subgroup.

Talbot and team also further investigated previous findings of a circadian rhythm effect on radiation response, reporting results that have also been published in Clinical Oncology .

Anthracycline exposure in young adults who previously received cancer treatment is associated with a significantly elevated risk for heart failure.

“These associations persisted over some, but not all, types of cancer,” note the researchers in JAMA Oncology .

ICIs were also efficacious in this population, and although they showed “differential activity across cancer types,” the objective response rates (ORRs) followed the general trends seen in people without HIV, note the researchers in the Journal of Clinical Oncology .