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Octreotide 

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  1. 29-01-2018 | FDA | News | Article
    approvalsWatch

    Lutetium-177–dotatate granted US approval for GEP-NETs

    The US FDA granted approval for the treatment following a randomized clinical trial in 229 patients that demonstrated extended progression-free survival with 177 Lu–dotatate plus octreotide versus octreotide alone.

  2. 12-01-2017 | Neuroendocrine tumors | News | Article
    News in brief

    OS promise for 177Lu-dotatate in neuroendocrine tumors

    A prespecified interim analysis of the NETTER-1 trial suggests that treatment with lutetium-177–dotatate could prolong overall survival relative to high-dose octreotide long-acting repeatable in patients with metastatic midgut neuroendocrine tumors.

  3. 01-09-2017 | Neuroendocrine tumors | Article

    Improving quality of life in patients with pancreatic neuroendocrine tumor following peptide receptor radionuclide therapy assessed by EORTC QLQ-C30

    In this study, the authors find peptide receptor radionuclide therapy to be effective in the treatment of pancreatic neuroendocrine tumors whilst also improving the quality of life of patients. Marinova M, et al. Eur J Nucl Med Mol Imaging 2017. doi:10.1007/s00259-017-3816-z

  4. 17-08-2017 | EMA | Drug approval | Article
    approvalsWatch

    Multiple orphan medications get nod from EMA

    The decision is based on results showing improved progression-free survival with 177 Lu-oxodotreotide over the somatostatin receptor agonist octreotide LAR in this patient population. --- The committee has recommended granting a marketing authorization to avelumab for the treatment of adults with metastatic Merkel cell carcinoma.

  5. 01-09-2016 | Neuroendocrine tumors | Book chapter | Article

    Targeted therapies for neuroendocrine neoplasms

    In this chapter, Soares and Strosberg describe the currently available targeted therapies for neuroendocrine tumors and review the clinical status of promising investigational therapies. Soares HP & Strosberg J. In:  Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances . Edited by Nasir A & Coppola D. Springer New York, 2016. doi:10.1007/978-1-4939-3426-3_28

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