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Neuroendocrine tumors 

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  1. 02-04-2019 | Neuroendocrine tumors | News | Article

    Potential of dual checkpoint blockade shown for neuroendocrine tumors

    Patients with high-grade neuroendocrine tumors may benefit from combined treatment with the PD-1 inhibitor nivolumab and the anti-CTLA-4 agent ipilimumab, indicate phase II results.

  2. 20-02-2017 | Neuroendocrine tumors | Article

    Radionuclide therapy for neuroendocrine tumors

    This review summarizes and considers possible strategies to further enhance the clinical efficacy of peptide receptor radionuclide therapy in gastroenteropancreatic and lung neuroendocrine tumors.  Cives M & Strosberg J. Curr Oncol Rep 2017; 19: 9. doi:10.1007/s11912-017-0567-8

  3. 01-09-2016 | Neuroendocrine tumors | Book chapter | Article

    Neuroendocrine tumors of the esophagus

    This chapter discusses the genetic and epigenetic alterations and molecular pathway dysregulations that are proposed to be involved in the pathogenesis of esophageal neuroendocrine tumors. Seydafkan S & Coppola D. In:  Neuroendocrine Tumors: Review of Pathology, Molecular and Therapeutic Advances . Edited by Nasir A & Coppola D. Springer New York, 2016. doi:10.1007/978-1-4939-3426-3_11

  4. 04-08-2017 | Neuroendocrine tumors | Article

    Challenges staging neuroendocrine tumors of the pancreas, jejunum and ileum, and appendix

    Here, changes in the 8th edition of the AJCC staging system for neuroendocrine tumors of the pancreas, jejunum/ileum, and appendix are highlighted. Nakakura EK. Ann Surg Oncol . 2017. doi:10.1245/s10434-017-6026-9

  5. 13-03-2017 | Neuroendocrine tumors | Article

    Treatment strategies for metastatic neuroendocrine tumors of the gastrointestinal tract

    This review summarizes recent advances in the therapy of advanced gastroenteropancreatic-neuroendocrine tumors, delineating possible approaches for the management of this heterogeneous group of malignancies. Cives M & Strosberg J.  Curr Treat Options in Oncol 2017; 18: 14. doi:10.1007/s11864-017-0461-5

  6. 12-01-2017 | Neuroendocrine tumors | News | Article
    News in brief

    OS promise for 177Lu-dotatate in neuroendocrine tumors

    A prespecified interim analysis of the NETTER-1 trial suggests that treatment with lutetium-177–dotatate could prolong overall survival relative to high-dose octreotide long-acting repeatable in patients with metastatic midgut neuroendocrine tumors.

  7. 13-09-2016 | Neuroendocrine tumors | Article

    Lanreotide Depot: An antineoplastic treatment of carcinoid or neuroendocrine tumors

    Wolin et al. outline how lanreotide depot provides potential advantages to both patients and healthcare providers in the treatment of gastroenteropancreatic neuroendocrine tumors. Wolin EM et al. J Gastrointest Canc 2016; 47: 366–374. doi:10.1007/s12029-016-9866-9

  8. 23-06-2016 | Neuroendocrine tumors | Article

    Somatostatin receptor PET/MRI for the evaluation of neuroendocrine tumors

    The review discusses the imaging of neuroendocrine tumors, which, with the increased availability of somatostatin receptor-targeted positron emission tomography tracers, has refocused on targeted imaging. Hope TA et al. Clin Transl Imaging 2017; 5: 63–69. doi:10.1007/s40336-016-0193-8

  9. 01-01-2015 | Neuroendocrine tumors | Book chapter | Article

    Epidemiology of neuroendocrine tumors

    The incidence and prevalence of neuroendocrine tumors has increased about four-fold in the last 30 years due to diagnostic improvements. The authors provide a summary of the available epidemiological data. Kilickap S & Hayran KM. In: Neuroendocrine Tumours . Edited by Yalcin S & Öberg K. Springer Berlin Heidelberg, 2015. doi:10.1007/978-3-662-45215-8_3

  10. 06-12-2016 | Neuroendocrine tumors | Article

    Patient-reported outcomes and quality of life with sunitinib versus placebo for pancreatic neuroendocrine tumors: results from an international Phase III trial

    Vinik et al. examined the health-related quality of life (HRQoL) of sunitinib-treated patients with pancreatic neuroendocrine tumors and found that survival increased without adversely affecting HRQoL. Vinik A et al. Targ Oncol 2016; 11: 815–824. doi:10.1007/s11523-016-0462-5

  11. 26-10-2023 | Toxicities | Teaser

    Looking for coverage of ESMO 2023?

    There's a new home for news and congress coverage! Catch up on all the top stories and latest evidence in oncology research with our ESMO congress hub page.  Learn more »

  12. 22-09-2023 | KRAS inhibitors | News | Article

    Novel KRAS inhibitor elicits ‘durable responses’ in KRAS G12C mutation-positive tumors

    The novel KRAS inhibitor divarasib has shown promise in previously treated patients with advanced solid tumors harboring a KRAS G12C mutation.

  13. 19-01-2016 | Neuroendocrine tumors | Article

    Association between general self-efficacy, social support, cancer-related stress and physical health-related quality of life: a path model study in patients with neuroendocrine tumors

    General self-efficacy, social support, and cancer-related stress are key factors in coping with a neuroendocrine tumor diagnosis. This study found that improving these factors may improve health-related quality of life. Haugland T et al. Health Qual Life Outcomes 2016; 14: 11. doi:10.1186/s12955-016-0413-y

  14. 09-08-2018 | FDA | News | Article
    approvalsWatch

    Iobenguane I-131 approved in USA for rare neuroendocrine tumor

    Read about this FDA announcement here

  15. 01-09-2017 | Neuroendocrine tumors | Article

    Improving quality of life in patients with pancreatic neuroendocrine tumor following peptide receptor radionuclide therapy assessed by EORTC QLQ-C30

    In this study, the authors find peptide receptor radionuclide therapy to be effective in the treatment of pancreatic neuroendocrine tumors whilst also improving the quality of life of patients. Marinova M, et al. Eur J Nucl Med Mol Imaging 2017. doi:10.1007/s00259-017-3816-z

  16. 25-07-2017 | Neuroendocrine tumors | Article

    Neuroendocrine liver metastasis: prognostic implications of primary tumor site on patients undergoing curative intent liver surgery

    A propensity score-matched analysis was  here utilized to assess the impact of primary tumor location on prognosis of patients undergoing curative intent liver resection for neuroendocrine liver metastasis. Spolverato G  et al. J Gastrointest Surg . 2017. doi: 10.1007/s11605-017-3491-1

  17. 09-02-2017 | Neuroendocrine tumors | Article

    Web-based information and support for patients with a newly diagnosed neuroendocrine tumor: a feasibility study

    The authors investigated whether the use of a web-based system, involving self-screening, patient education, and self-referral to professional healthcare, is feasible in patients with neuroendocrine tumors. Bouma G et al. Support Care Cancer 2017; 25: 2075–2083. doi:10.1007/s00520-017-3598-7

  18. 17-08-2021 | FDA | News | Article
    approvalsWatch

    FDA approves HIF-2α inhibitor belzutifan for VHL-associated tumors

    Specifically, the hypoxia-inducible factor-2α inhibitor may now be given to adults with VHL-associated renal cell carcinoma (RCC), central nervous system (CNS) hemangioblastomas, or pancreatic neuroendocrine tumors (pNETs) that do not need immediate surgery.

  19. 23-07-2020 | Lung cancer | News | Article
    News in brief

    Lung cancer COVID-19 guidance available

    The team details a recommended “workflow to standardize the delivery of multidisciplinary care” for patients with non-small-cell and small-cell lung cancer and neuroendocrine tumors, covering topics ranging from diagnosis to the management of metastatic disease.

  20. 21-12-2018 | Non-small-cell lung cancer | News | Article

    Clinical course of EGFR-mutant NSCLC transforming to SCLC documented

    To address this, they performed a retrospective chart review of 67 patients (median age 56 years, 57% women) with EGFR -mutant SCLC or high-grade neuroendocrine carcinoma.

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