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35 search results for:

Endometrial carcinoma 

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  1. 04-08-2017 | Ovarian cancer | Article

    Molecular-based classification algorithm for endometrial carcinoma categorizes ovarian endometrioid carcinoma into prognostically significant groups

    ​​​​​​​ Mod Pathol 2017. doi:10.1038/modpathol.2017.81

    Author:
    Carlos Parra-Herran, Jordan Lerner-Ellis, Bin Xu, Sam Khalouei, Dina Bassiouny, Matthew Cesari, Nadia Ismiil, Sharon Nofech-Mozes
  2. 22-09-2023 | KRAS inhibitors | News | Article

    Novel KRAS inhibitor elicits ‘durable responses’ in KRAS G12C mutation-positive tumors

    This included three patients with pancreatic adenocarcinoma and one patient each with anal adenocarcinoma, cholangiocarcinoma, endometrial squamous-cell carcinoma, large-cell neuroendocrine carcinoma of the lung, and stomach adenocarcinoma.

    Author:
    Shreeya Nanda
    Published in:
    N Engl J Med 2023; 389 : 710–721
  3. 14-12-2020 | SABCS 2020 | Conference coverage | Article

    ​​​​​​​IBIS-II update shows no difference in anastrozole, tamoxifen efficacy in DCIS

    Long-term results from the IBIS-II trial show a comparable risk for breast cancer recurrence with anastrozole and tamoxifen among postmenopausal women with hormone receptor-positive ductal carcinoma in situ.

    Author:
    Hannah Kitt
    Published in:
    SABCS 2020: 8–11 December
  4. 30-01-2020 | Renal cell carcinoma | News | Article

    Lenvatinib plus pembrolizumab shows promise for RCC and other solid tumors

    Phase 1b/2 study data show that combining the multitargeted tyrosine kinase inhibitor lenvatinib with pembrolizumab could be a promising treatment option for patients with advanced renal cell carcinoma and selected other advanced solid tumor types.

    Author:
    Laura Cowen
    Published in:
    J Clin Oncol 2020; doi:10.1200/JCO.19. 01598
  5. 09-12-2019 | Prostate cancer | News | Article

    Nivolumab shows promise in ‘wide variety’ of mismatch repair-deficient cancers

    The most common tumors were endometrial and prostate adenocarcinoma, seen in 13 and five patients, respectively.

    Published in:
    J Clin Oncol 2019; doi:10.1200/JCO.19.00818
  6. 31-08-2018 | Breast cancer | News | Article

    In other news: Breast cancer treatment effects

    The focus this month is on early and late treatment effects in patients with breast cancer, including effects on endometrial cancer risk, cardiotoxicity, and skin toxicity.

  7. 07-12-2018 | Risk factors | News | Article
    News in brief

    Polycystic ovary syndrome associated with increased cancer risk

    Women with polycystic ovary syndrome may have an increased likelihood for developing cancer, although the excess risk appears to be primarily restricted to those who are premenopausal, indicates a population-based study.

  8. 23-02-2018 | Endometrial carcinoma | News | Article

    Women with stage III endometrial cancer may benefit from adjuvant chemoradiotherapy

    Adding chemotherapy during and after radiotherapy may benefit some women with stage III endometrial cancer, indicate findings from the PORTEC-3 trial. Click for the view of gynecologic oncology expert Ramez Eskander

    Published in:
    Lancet Oncol 2018; Advance online publication
  9. 14-02-2018 | PI3K inhibitors | News | Article

    Early alpelisib data promising in patients with PIK3CA-altered solid tumors

    Responses occurred at once daily doses of 270 mg or higher, and included one complete response in a patient with endometrial cancer and seven partial responses in patients with cervical, breast, endometrial, colon, and rectal cancers.

    Published in:
    J Clin Oncol 2018; Advance online publication
  10. 21-08-2017 | Uterine cancer | Article

    Sentinel lymph node mapping in endometrial cancer: comparison of fluorescence dye with traditional radiocolloid and blue

    In this review, Papadia et al discuss and compare the different types of tracers adopted for sentinel lymph node mapping in patients with endometrial cancer, including cost-effectiveness, quality of care and toxicity.  Papadia A et al. J Cancer Res Clin Oncol 2017; 143: 2039–2048. doi:10.1007/s00432-017-2501-8

  11. 01-09-2017 | Uterine cancer | Article

    Cardiovascular disease mortality among women with endometrial cancer in the Iowa Women’s Health Study

    Examining a prospective cohort study, the authors shed new light on the association between endometrial cancer development and cardiovascular disease mortality.  Felix AS et al. Cancer Causes Control 2017; 28: 1043-1051. doi:10.1007/s10552-017-0953-4

  12. 08-07-2017 | Uterine cancer | Article

    Tailoring Adjuvant Radiotherapy in Endometrial Cancer

    This study examines the patterns of failure following adjuvant radiotherapy in patients with endometrial cancer according to the extent of the disease and risk groups. Narayan K et al. Indian J Gynecol Oncolog 2017; 15: 45. doi:10.1007/s40944-017-0136-y

  13. 06-07-2017 | Uterine cancer | Article

    Commonly used medications and endometrial cancer survival: a population-based cohort study

    This large UK prospective cohort study is the first to assess the relationship between the use of β-blockers and endometrial cancer-specific mortality, as well two other possible adjuvant therapies, statins and aspirin. Br J Cancer  2017; 117: 432–438. doi:10.1038/bjc.2017.207

    Author:
    Omolara B Sanni, Úna C McMenamin, Chris R Cardwell, Linda Sharp, Liam J Murray, Helen G Coleman
  14. 15-06-2017 | Uterine cancer | Article

    Radiation-related toxicities and outcomes in endometrial cancer: are obese women at a disadvantage?

    Smits et al report a retrospective cohort study which is one of the first to shed light on how the BMI of women diagnosed with endometrial cancer affects the toxicity of radiotherapy they receive and hence survivor quality of life. Smits A et al. Int J Clin Oncol 2017; 22: 945. doi:10.1007/s10147-017-1147-5

  15. 25-11-2016 | Ovarian cancer | Article

    The disparate origins of ovarian cancers: pathogenesis and prevention strategies

    The clonal relationship of synchronous endometrial and ovarian ECs supports this notion 78 .

    Author:
    Anthony N. Karnezis, Kathleen R. Cho, C. Blake Gilks, Celeste Leigh Pearce, David G. Huntsman
  16. 13-04-2017 | Endometrial carcinoma | News | Article
    News in brief

    Laparoscopic hysterectomy supported for early endometrial cancer

    The phase III LACE trial shows that total laparoscopic hysterectomy for stage I endometrial cancer is equivalent to total abdominal hysterectomy with respect to disease-free survival.

  17. 08-03-2017 | Uterine cancer | Book chapter | Article

    Endometrial cancer

    Fertility preservation is a big issue for cancer survivors and it is necessary to realize that treatment decisions are being made thinking on future fertility. This chapter reviews endometrial cancer diagnosis, risk factors, treatments, and fertility preservation options. Goetsch AL, Kimelman D, & Woodruff TK. In:  Fertility Preservation and Restoration for Patients with Complex Medical Conditions . Springer International Publishing, 2017. doi:10.1007/978-3-319-52316-3_18

  18. 11-11-2016 | Uterine cancer | Article

    FIGO stage IIIC endometrial cancer identification among patients with complex atypical hyperplasia, grade 1 and 2 endometrioid endometrial cancer: laparoscopic indocyanine green sentinel lymph node mapping versus frozen section of the uterus, why get around the problem?

    This study compares the efficacy of two surgical strategies used to identify lymph node metastases in patients with preoperative diagnosis of complex atypical hyperplasia, and grade 1 and 2 endometrial cancer. Papadia A et al. J Cancer Res Clin Oncol 2017; 143: 491–497. doi:10.1007/s00432-016-2303-4

  19. 26-05-2016 | Uterine cancer | Article

    Long term follow-up of a phase II trial of multimodal therapy given in a “sandwich” method for stage III, IV, and recurrent endometrial cancer

    The aim of this study was to determine if overall survival and progression-free survival rates are maintained long term following multimodal therapy for advanced and recurrent endometrial cancer and to assess the associated lymphedema rates. Glasgow M et al. Gynaecol Oncol Res Pract 2016; 3: 6. doi:10.1186/s40661-016-0027-4

  20. 27-02-2016 | Uterine cancer | Article

    What is the best preoperative imaging for endometrial cancer?

    In this review the authors summarize the reported staging performances of conventional and novel preoperative imaging methods and provide an overview of promising novel imaging methods relevant for endometrial cancer care. Haldorsen IS & Salvesen HB. Curr Oncol Rep 2016; 18: 25. doi:10.1007/s11912-016-0506-0

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