Older individuals with a history of cancer, especially those with a more recent diagnosis, have a higher risk for frailty-related bone fractures than their cancer-free counterparts, suggests a large longitudinal study.

Authors:  Danielle Brazel, Gianna Kroening & Misako Nagasaka Abstract  Molecular testing is performed upon diagnosis of non-small cell lung cancer (NSCLC) because of the large success of targeted therapies for oncogenic mutations.

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An analysis of the CCC19 registry has demonstrated a significant link between receipt of anticancer therapies within 3 months of a COVID-19 diagnosis and an elevated risk for venous thromboembolism

They add: “For instance, increased lymph node involvement is often seen in IBCs and cannot be accounted for entirely by delayed diagnosis but rather may be due to a unique biology.”

They hope that by quantifying the impact on breast cancer screening, diagnosis, and treatment, the findings may “alter the management of future outbreaks and illuminate the current path to normalization.”

Preliminary MASAI trial results indicate that AI-supported mammography has a similar rate of breast cancer detection to standard double reading while reducing the screen-reading workload.

Pregnancy-associated cancers may be linked to an elevated 5-year mortality risk, but the risk varies by tumor site and time of diagnosis, suggests a population-based cohort study.

This equated to a 2.6-fold increased risk with anthracycline exposure after accounting for age, sex, race/ethnicity, history of hypertension or CVD, and secondary cancer diagnosis.

“This further reinforces the need to identify these patients with available biomarkers at the time of diagnosis and before treatment begins.”

The use of immune checkpoint inhibitors is not associated with excess toxicity in people living with HIV and a concomitant diagnosis of cancer, indicate real-world results.