2021 ASCO Annual Meeting

Matteo Lambertini comments on the early and advanced breast cancer trials that caught his attention at the 2021 ASCO Annual Meeting, including the OlympiA, ECOG-ACRIN EA1131, GeparNUEVO, DAWNA-1, and sysucc-002 studies.

Jennifer Litton discusses results of the NEOTALA trial suggesting patients with germline BRCA1/2-mutant, HER2-negative, early breast cancer may benefit from neoadjuvant treatment with talazoparib.

Ingrid Mayer discusses findings from the ECOG-ACRIN EA1131 trial showing no benefit of postoperative platinum-based chemotherapy versus capecitabine in patients with triple-negative breast cancer who have residual disease following neoadjuvant chemotherapy.

Petros Grivas outlines the latest analyses of the JAVELIN Bladder 100 study of maintenance avelumab in metastatic urothelial cancer, including the assessment of efficacy by clinical and molecular subgroups and by the post-chemotherapy treatment-free interval, as well as data on time to end of subsequent therapy.

This independent video interview was supported by an educational grant from Pfizer and Merck Healthcare KGaA, Darmstadt, Germany

Arjun Balar talks through the INDUCE-1 trial findings for patients with advanced urothelial carcinoma who were given the ICOS agonist feladilimab alone or alongside pembrolizuamb.

This independent video interview was supported by an educational grant from Pfizer and Merck Healthcare KGaA, Darmstadt, Germany

Peter O’Donnell gives an update on the KEYNOTE-052 trial findings for first-line pembrolizumab in cisplatin-ineligible patients with advanced urothelial carcinoma.

This independent video interview was supported by an educational grant from Pfizer and Merck Healthcare KGaA, Darmstadt, Germany

Gilberto Lopes shares his lung cancer highlights from the 2021 ASCO Annual Meeting, including the IMpower010 trial, the MYLUNG study of real-world molecular testing, and updates on the CodeBreaK 100 and CHRYSALIS studies.

Heather Wakelee talks through the efficacy and safety data from the IMpower010 study of postoperative atezolizumab in individuals with early-stage non-small-cell lung cancer, touching on the cost aspect and outlining the key unanswered questions.

Stephen Liu talks through the latest findings from the ARROW trial of pralsetinib for patients with RET fusion-positive advanced non-small-cell lung cancer.