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2 search results for:

Selinexor 

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  1. 09-02-2018 | Multiple myeloma | News | Article

    Selinexor shows efficacy against refractory multiple myeloma

    One in five patients with heavily pretreated, refractory multiple myeloma may respond to treatment with the selective exportin 1 inhibitor selinexor, plus low-dose dexamethasone, phase II study findings indicate.

    Published in:
    J Clin Oncol 2018; Advance online publication
  2. 12-08-2016 | Acute lymphoblastic leukemia | Article

    A review of new agents evaluated against pediatric acute lymphoblastic leukemia by the Pediatric Preclinical Testing Program

    This may have been the case for agents achieving objective responses in <50% of PDXs tested, such as selinexor (objective responses (OR)/ N =2/8), dinaciclib (OR/ N =2/7), rapamycin (OR/ N =2/8) and JNJ-26481585 (OR/ N =2/8), therefore follow-up testing on these agents is warranted to identify biomarkers of the response.

    Author:
    L Jones, H Carol, K Evans, J Richmond, P J Houghton, M A Smith, R B Lock
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