Skip to main content
Latest news
Browse specialties
Breast cancer Genitourinary cancers Lung & thoracic cancers
In focus
Next-generation sequencing: Emerging biomarkers in thyroid and NSCLCs ctDNA and bladder cancer: Current understanding and beyond ROS1 fusion-positive NSCLC NSCLC driver mutations: Discussing the importance of RET, ALK and ROS1 alterations in NSCLC Early-stage NSCLC management: Surgery, targeted treatment and immunotherapy ALK fusion-positive NSCLC: International approaches to management RET fusion-positive NSCLC: Informing on the use of pralsetinib for patients with RET fusion-positive, advanced NSCLC COVID-19 & cancer
Conferences
SABCS 2022 ESMO 2022 2022 ASCO Annual Meeting
About us
Medicine Matters Oncology
EXTENDED SEARCH
10 search results for:

Proteosome inhibitors 

sort by |
"newest" sorts results by publication date. "most relevant" also considers factors like how often the search phrase is in the result.
  1. 21-10-2016 | Treatment | Article

    The role of maintenance therapy in multiple myeloma

    More recently, the landscape of MM therapy continues to expand further with the approval of next generation proteasome inhibitors and immunomodulatory agents as well as the recent approval of new drugs with novel mechanisms of action including monoclonal antibodies and histone deacetylase inhibitors. 15, 16, 17  With the rapid changes in MM therapy, our goal with this review is to analyze the current literature and provide recommendations for maintenance therapy in MM, primarily with lenalidomide and bortezomib.

    Author:
    B Lipe, R Vukas, J Mikhael
  2. 25-10-2017 | Acute leukemia | Article

    (Immuno)proteasomes as therapeutic target in acute leukemia

    The authors summarize the positioning of bortezomib, a first-generation proteasome inhibitor, and second-generation proteasome inhibitors in leukemia treatment from a preclinical and clinical perspective. Cloos J, Roeten MS, Franke NE et al. Cancer Metastasis Rev 2017. doi:10.1007/s10555-017-9699-4

  3. 06-09-2017 | Multiple myeloma | News | Article
    News in brief

    Carfilzomib boosts OS in relapsed, refractory multiple myeloma patients

    The combination of carfilzomib and dexamethasone should be considered a standard of care in patients with relapsed or refractory multiple myeloma, say researchers who conducted a head to head comparison with bortezomib plus dexamethasone.

  4. 14-08-2017 | FDA | News | Article
    approvalsWatch

    Carfilzomib accepted by SMC for relapsed multiple myeloma

    Read more about this advisory here

  5. 24-01-2017 | Multiple myeloma | Article

    Proteasome inhibitors in cancer therapy

    This review analyzes the latest advances and challenges resulting from the introduction of proteasome inhibitors into the clinical setting for patients with multiple myeloma. Nat Rev Clin Oncol 2017. doi:10.1038/nrclinonc.2016.206

    Author:
    Elisabet E. Manasanch, Robert Z. Orlowski
  6. 30-06-2016 | Multiple myeloma | Article

    Novel agents in the treatment of multiple myeloma: a review about the future

    The authors review the plethora of novel agents currently in development or recently approved for the treatment of patients with multiple myeloma. Naymagon L & Abdul-Hay M. J Hematol Oncol 2016; 9: 52. doi:10.1186/s13045-016-0282-1

  7. 22-01-2016 | Treatment | Article

    Immune responses in multiple myeloma: role of the natural immune surveillance and potential of immunotherapies

    Here, Guillerey et al. review the immunological microenvironment in myeloma and highlight the numerous promising immune-targeting strategies approved or in clinical trials for the treatment of myeloma. Guillerey C, Nakamura K, Vuckovic S, Hill GR, Smyth MJ.  Cell Mol Life Sci  2016; 73:1569–1589. doi: 10.1007/s00018-016-2135-z

  8. 19-02-2016 | Treatment | Article

    Smoldering multiple myeloma: emerging concepts and therapeutics

    This review focuses on advances in the smoldering multiple myeloma risk-stratification model and recent clinical trials in this patient population. Sundararajan S, Kumar A, Korde N, Agarwal A. Curr Hematol Malig Rep  2016; 11: 102–110. doi: 10.1007/s11899-016-0305-6

  9. 15-08-2015 | Treatment | Article

    Novel induction regimens in multiple myeloma

    The focus of this review is a critical analysis of combinations of novel agents in the treatment of newly diagnosed multiple myeloma in both transplant eligible and ineligible patients. Runcie KD & Mark TM. Curr Hematol Malig Rep 2015; 10: 388–394. doi:10.1007/s11899-015-0282-1

  10. 03-02-2015 | Treatment | Article

    Treatment-related symptom management in patients with multiple myeloma: a review

    This review discusses current multiple myeloma treatment options, effective symptom management approaches, and practical strategies for supportive care. Colson K. Support Care Cancer 2015; 23: 1431–1445. doi:10.1007/s00520-014-2552-1

  • 1

Filter search results

Search Operators:

„ ... ... “ Finds documents with exactly this word group, in exactly this word order and spelling (e.g., "employer branding").
AND Finds documents with both search terms (e.g., sales AND bonus).
OR Finds documents with one or the other search term (e.g., porsche OR volkswagen).
Blank Space Finds documents with all search terms. Blank space is understood as AND (e.g., man robot production).
NOT Finds documents with no appearance of the word behind NOT (e.g., ford NOT "harrison ford").
COUNT(...)>n Finds documents where the search term is mentioned at least "n" times."n" may be any number (e.g., COUNT(gear)>8).
NEAR(..., ..., ) Finds documents with both search terms in any word order, permitting "n" words as a maximum distance between them. Best choose between 15 and 30 (e.g., NEAR(recruit, professionals, 20)).
* Finds documents with the search term in word versions or composites. The star * marks whether you wish them BEFORE, BEHIND, or BEFORE and BEHIND the search term (e.g., lightweight*, *lightweight, *lightweight*).
? Finds documents with the search termn in different spellings."?" allows only one character (e.g., organi?ation).
& + - Special characters are understood as AND (e.g., Miller Bros. & Sons).

You can use operators in your search query to narrow down your results even more.

Tap the operator, or hover the mouse pointer over it, to read more about how it works.