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Medicine Matters oncology

AFM13 is a bispecific, tetravalent chimeric antibody (TandAb) construct that recruits natural killer (NK) cells via CD16A binding and also targets CD30+ malignancies. Preliminary data from a phase IB/IIA study has shown that treatment with AFM13-induced responses in two out of three patients with CD30+ cutaneous lymphoma who failed at least one prior therapy.