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In depth

In depth

28-02-2019 | Lung cancer | At a glance | Article

At a glance: CheckMate lung cancer trials

Here we round up the CheckMate trials evaluating the PD-1 inhibitor nivolumab in non-small-cell lung cancer and small-cell lung cancer.

28-01-2019 | Immunotherapy | Podcast | Audio

Understanding the relationship between the gut microbiome and immunotherapy

Jennifer Wargo, from The University of Texas MD Anderson Cancer Center in Houston, USA, shares her insights into recent research showing an association between intestinal microbiota and response to immunotherapy (13:27).

28-01-2019 | Immunotherapy | At a glance | Article

Gut microbiota and immunotherapy response: A round-up of the trials

A round-up of the key studies – all published in Science – that have investigated the association between the gut microbiome and response to immune checkpoint inhibitors.

12-12-2018 | Immunotherapy | Feature | Article

Hyperprogression as a response to immunotherapy: ‘A serious downside’

In light of recent reports of hyperprogression in response to treatment with cancer immunotherapy, medwireNews spoke to medical oncologist Razelle Kurzrock (University of California, San Diego, La Jolla, USA) about the phenomenon, the implications for therapy, and future directions for research.

15-11-2018 | Prostate cancer | Podcast | Audio

Researcher comment: COMPARE study

Hashim Ahmed takes us through the COMPARE study – presented at NCRI 2018 – which showed that men with localized prostate cancer are willing to make accept lower survival odds for a better quality of life. He outlines the key findings, the implications of the results for physicians, and the next steps for research (5:36).

Click here for the accompanying news story.

15-10-2018 | Acute lymphoblastic leukemia | Podcast | Audio

ALL and infection: Unpicking the connection

Mel Greaves (Institute of Cancer Research, London, UK) discusses his proposed theory for the etiology of childhood acute lymphoblastic leukemia, in which early microbial exposure plays a key role (10:21).

27-04-2018 | Adolescents and young adults | Feature | Article

ACCELERATE-ing access to drugs for adolescents with cancer

medwireNews spoke to Miranda Fidler, from the International Agency for Research on Cancer, and Simon Davies, from Teen Cancer America, about the ACCELERATE working group's proposal to improve adolescent patients’ access to new cancer drugs.

Click for the accompanying news story

05-04-2018 | Uveal melanoma | Podcast | Audio

SUMIT: Selumetinib in metastatic uveal melanoma

This edition of the medwireNews podcast focuses on a recent trial of the MEK inhibitor selumetinib in metastatic uveal melanoma. Advisory Board member and study author Paul Nathan outlines the findings and discusses the wider implications.

01-02-2018 | Malignant pleural effusion | Podcast | Audio

Expert comment: AMPLE trial

Listen to Fabien Maldonado, from Vanderbilt University Medical Center in Nashville, Tennessee, USA, give his views on the AMPLE trial, which aimed to establish the more effective technique for reducing the number of hospitalization days in patients with malignant pleural effusion.

20-12-2017 | Epidemiology | Feature | Article

Expert comment: Global cancer incidence and mortality in young adults

Lorna Fern, from UK's National Cancer Research Institute, provides an independent comment on a recent study reporting on the global young adult cancer burden and discusses the key challenges for this population group.

Read the related news story

12-09-2017 | Cervical cancer | Podcast | Audio

Bevacizumab in cervical cancer

The phase III GOG 240 trial evaluated bevacizumab in women with advanced cervical cancer - Advisory Board member and lead investigator Krishnansu Tewari outlines the results of the final analysis in this podcast.

08-08-2017 | Non-small cell lung cancer | At a glance | Article

At a glance: The KEYNOTE lung cancer trials

Here is our updated quick-access guide to the KEYNOTE trials investigating the anti-PD-1 agent pembrolizumab in the non-small-cell and small-cell lung cancer settings.

Updated July 2019

21-04-2017 | Lymphoma | Feature | Article

Lymphoma in practice: Professor Anas Younes speaks to medwireNews

Professor Anas Younes tells medwireNews about the current issues in lymphoma practice, both for the clinician and patients.

01-02-2017 | Patient-reported outcomes | Feature | Article

The time is right for patient-reported outcomes

medwireNews talks to Professor Dame Lesley Fallowfield and Dr Ethan Basch about the barriers to the routine incorporation of patient-reported outcomes in oncology clinical trials, and the changes that are happening.

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