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01-01-2016 | Endocrine cancers | Book chapter | Article

14. The Role of Risk Stratification in the Treatment of Well-Differentiated Thyroid Cancer

Author: M.D., F.A.C.S. Kepal N. Patel

Publisher: Springer International Publishing

Abstract

The primary goal in the management of patients with well-differentiated thyroid cancer is to provide the best therapy with the least amount of morbidity. Initial therapy to remove all gross disease should be based on a risk adapted approach. The follow-up paradigm should incorporate the initial risk assessment, ongoing risk stratification, response to therapy variables, and disease-free survival. It is a dynamic process which helps ensure optimal patient care by allowing physicians to identify patients who are at high risk for disease recurrence. These patients may benefit from closer surveillance, testing, and treatment. More importantly, this dynamic risk adapted paradigm will help avoid over-treatment in patients who are at low risk of recurrence.

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