Edelman MJ et al. J Clin Oncol 2017; 35(19): 2184-2192. doi: 10.1200/JCO.2016.71.3743 Please follow the link below to view this article in full on a third party website. Note that a subscription or payment may be required. http://ascopubs.org/doi/full/10.1200/JCO.2016.71.3743