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Triple-negative breast cancer

Journal articles and book chapters

08-01-2018 | Triple-negative breast cancer | Article

Clinical and pathological factors influencing survival in a large cohort of triple-negative breast cancer patients

Urru SAM et al. BMC Cancer 2018; 18: 56. doi:10.1186/s12885-017-3969-y

06-11-2017 | Triple-negative breast cancer | Article

Role of Platinum in Early-Stage Triple-Negative Breast Cancer

La Belle A et al. Curr Treat Options in Oncol 2017; 18: 68. doi:10.1007/s11864-017-0506-9

03-10-2017 | Breast cancer | Article

Discrepancies between biomarkers of primary breast cancer and subsequent brain metastases: an international multicenter study

Kaidar-Person, Meattini I, Jain P et al. Breast Cancer Res Treat 2017. doi:10.1007/s10549-017-4526-8

27-11-2016 | Triple-negative breast cancer | Book chapter | Article

Triple-negative breast cancer

This book chapter explores newly-discovered molecular subtypes of triple-negative breast cancer and how genetic profiling can be used to target therapy.

Telli ML. In: Molecular Pathology of Breast Cancer. Edited by Badve S and Gökmen-Polar Y. Springer, Cham, 2016. doi:10.1007/978-3-319-41761-5_6

16-11-2016 | Triple-negative breast cancer | Article

Triple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants

Triple-negative breast cancer (TNBC) is a vastly heterogeneous disease. This review focuses on the histologic and molecular features of low-grade forms of TNBC.

npj Breast Cancer 2016;2:16036. doi:10.1038/npjbcancer.2016.36

10-07-2016 | Triple-negative breast cancer | Article

Concepts and targets in triple-negative breast cancer: Recent results and clinical implications

The discovery of subsets of triple-negative breast cancer has driven research focusing on targeted therapies. This review article provides an overview of recent developments.

Saha P and Nanda R. Ther Adv Med Oncol 2016;8:351–359. doi:10.1177/1758834016657071

17-05-2016 | Triple-negative breast cancer | Article

Triple-negative breast cancer: Challenges and opportunities of a heterogeneous disease

​​​​​​​Nat Rev Clin Oncol 2016;13: 674-690. doi:10.1038/nrclinonc.2016.66

03-10-2015 | Triple-negative breast cancer | Article

Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response

This study analyzed biopsies and blood samples of patients with triple-negative breast cancer in an attempt to find chemotherapy response-predictive biomarkers and to identify new treatment targets.

Lips EH, Michaut M, Hoogstraat M et al. Breast Cancer Res 2015;17:134. doi:10.1186/s13058-015-0642-8

23-07-2015 | Triple-negative breast cancer | Article

Androgen receptor biology in triple negative breast cancer: A case for classification as AR+ or quadruple negative disease

Barton VN, D’Amato NC, Gordon MA et al. Horm Canc 2015;6:206–213. doi:10.1007/s12672-015-0232-3

20-03-2015 | Triple-negative breast cancer | Article

Gene-expression molecular subtyping of triple-negative breast cancer tumours: Importance of immune response

This study retrospectively analyzed the microarray gene-expression profiles of 107 triple-negative breast tumors in an attempt to better understand therapeutic subgroups.

Jézéquel P, Loussouarn D, Guérin-Charbonnel C et al. Breast Cancer Res 2015;17:43. doi:10.1186/s13058-015-0550-y

12-12-2014 | Triple-negative breast cancer | Article

Metabolic characterization of triple negative breast cancer

This study aimed to characterize the metabolite profiles of triple-negative breast cancer in comparison with ‘triple-positive’ breast cancer, and how this may help targeted treatment strategies.

Cao MD, Lamichhane S, Lundgren S et al. BMC Cancer 2014;14:941. doi:10.1186/1471-2407-14-941

05-06-2014 | Triple-negative breast cancer | Article

Molecular heterogeneity of triple-negative breast cancer

This review article describes the different subtypes of triple-negative breast cancer and potential therapeutic strategies and novel approaches to targeted therapy.

Abramson VG and Mayer IA. Curr Breast Cancer Rep 2014;6:154. doi:10.1007/s12609-014-0152-1