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3 search results for:

Sonidegib 

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  1. 28-01-2022 | Basal cell carcinoma | Adis Journal Club | Article
    Advances in Therapy

    New Emerging Treatment Options for Advanced Basal Cell Carcinoma and Squamous Cell Carcinoma

    Hedgehog inhibitors (HHIs) are promising alternative treatments for patients with advanced basal cell carcinomas; vismodegib and sonidegib, two oral smoothened (SMO) antagonists, have already been approved for the treatment of adult patients with advanced basal cell carcinoma Currently, US Food and Drug Administration (FDA) has granted Orphan Drug and Breakthrough Therapy Designation for topical patidegib gel formulation in patients with basal cell carcinoma nevus syndrome, also known as Gorlin syndrome Cemiplimab has been approved by the European Medicines Agency (EMA) and Food and Drug Administration (FDA) for the treatment of adult patients with metastatic or locally advanced cutaneous squamous cell carcinoma, not eligible for surgery or radiotherapy, and for adult patients with locally advanced or metastatic BCC intolerant to a HH pathway inhibitor

  2. 03-02-2015 | Basal cell carcinoma | Article

    Management of high-risk and advanced basal cell carcinoma

    An expert review of the management recommendations for high-risk and advanced basal cell carcinoma including surgical excision, Mohs micrographic surgery, radiotherapy, and novel agents in development. Puig S |& Berrocal A. Clin Transl Oncol 2015; 17: 497–503. doi:10.1007/s12094-014-1272-9

  3. 01-01-2015 | Non-melanoma skin cancer | Article

    Non-melanoma skin cancer: primary non-surgical therapies and prevention strategies

    In this chapter the authors present non-surgical treatment options for the two most common non-melanoma skin cancers basal cell and squamous cell carcinoma. Buchanan MA et al. In: Non-melanoma Skin Cancer of the Head and Neck . Edited by F Riffat, CE Palme, M Veness. India: Springer India, 2015. doi:10.1007/978-81-322-2497-6_4

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