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5 search results for:

Panitumumab 

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  1. 21-04-2020 | FDA | News | Article
    approvalsWatch

    Tucatinib combination approved for advanced HER2-positive breast cancer

    Read more on this FDA announcement here

    Author:
    Lynda Williams
  2. 10-07-2017 | FDA | News | Article
    approvalsWatch

    Dabrafenib–trametinib approved for metastatic BRAF V600E-positive NSCLC

    The test can detect 56 different KRAS and NRAS tumor mutations, the absence of which indicates patient suitability for treatment with the EGFR inhibitor panitumumab.

  3. 02-03-2017 | Liquid biopsy | Review | Article

    Integrating liquid biopsies into the management of cancer

    Indeed, Diaz and co-workers 2 uncovered the presence of multiple KRAS mutations in the circulation of single patients with metastatic colorectal cancer receiving panitumumab treatment.

    Author:
    Giulia Siravegna, Silvia Marsoni, Salvatore Siena, Alberto Bardelli
  4. 06-12-2016 | Colorectal cancer | Article

    From tumour heterogeneity to advances in precision treatment of colorectal cancer

    The benefit of chemotherapy is further increased by the addition of targeted drugs, such as bevacizumab, and in patients with  RAS -wild-type tumours, by the addition of cetuximab or panitumumab 26, 27, 28, 29, 30, 31 .

    Author:
    Cornelis J. A. Punt, Miriam Koopman, Louis Vermeulen
  5. 17-05-2016 | Triple-negative breast cancer | Article

    Triple-negative breast cancer: Challenges and opportunities of a heterogeneous disease

    Given this finding, and the long-standing availability of clinically approved inhibitors of EGFR (such as erlotinib, gefitinib, lapatinib, cetuximab and panitumumab), several trials have tested the efficacy of these agents in patients with TNBC.

    Author:
    Giampaolo Bianchini, Justin M. Balko, Ingrid A. Mayer, Melinda E. Sanders, Luca Gianni
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