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Nasopharyngeal tumors 

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  1. 15-03-2021 | COVID-19 | News | Article
    News in brief

    SARS-CoV-2 shedding may be prolonged in advanced solid cancer patients

    An early study of viral shedding in solid cancer patients with COVID-19 suggests that advanced tumors may be associated with prolonged infection compared with early-stage disease.

  2. 05-09-2017 | Pembrolizumab | News | Article

    KEYNOTE-028 results point to pembrolizumab efficacy in SCLC, nasopharyngeal cancer

    Findings from the multicohort, phase Ib KEYNOTE-028 trial indicate that pembrolizumab elicits durable responses and is well tolerated in patients with extensive-stage small-cell lung cancer and those with recurrent or metastatic nasopharyngeal carcinoma.

  3. 11-01-2021 | COVID-19 | News | Article

    COVID-19 rate ‘low’ in patients receiving anticancer therapy

    The most common tumor types in this group were lung cancer (22.4%) and breast cancer (18.5%), and nearly two-thirds (62.1%) of the patients were receiving chemotherapy or chemoimmunotherapy.

  4. 04-05-2018 | Nivolumab | News | Article

    In other news

    This month we bring you a round-up of four trials investigating nivolumab in diverse tumors, including non-small-cell lung cancer, Hodgkin lymphoma, and nasopharyngeal carcinoma. Read on to find out more.

  5. 24-08-2017 | Nasopharyngeal cancer | News | Article

    EBV DNA positivity may signify asymptomatic nasopharyngeal carcinoma

    Patients with plasma samples repeatedly positive for Epstein–Barr virus DNA should undergo further screening for nasopharyngeal carcinoma, researchers report.

  6. 02-04-2019 | Small-cell lung cancer | News | Article

    Pembrolizumab supported for third- or later-line extensive-stage SCLC

    The exploratory analysis included 19 patients from the phase Ib KEYNOTE-028 trial that restricted participation to those with PD-L1-positive tumors and 64 patients from the phase II KEYNOTE-158 trial that did not have any restrictions based on PD-L1 levels.

  7. 15-05-2018 | Head and neck cancers | News | Article

    HPV positivity may improve survival in some nonoropharyngeal head and neck cancers

    By contrast, HPV status had no impact on survival among patients with tumors in the nasopharynx or sinonasal tract.

  8. 24-02-2017 | Liquid biopsy | Review | Article

    Liquid biopsies come of age: Towards implementation of circulating tumor DNA

    For cancers with a viral aetiology — for example, nasopharyngeal carcinoma or cervical cancer — detection of the cancer-associated viral DNA that may be present in body fluids in many more copies than tumour DNA can enhance the identification of individuals with early-stage disease, or those with premalignant lesions and a high risk of cancer 143,144 .

  9. 02-03-2017 | Liquid biopsy | Review | Article

    Integrating liquid biopsies into the management of cancer

    For example, ctDNA analysis of Epstein–Barr virus (EBV) has been used for the early detection of nasopharyngeal carcinoma 126 .

  10. 05-07-2016 | Treatment | Article

    Definitive chemoradiation alters the immunologic landscape and immune checkpoints in head and neck cancer

    The larynx cancer patient demonstrated increased antibody titres directed against a diverse array of proteins that did include known tumour antigens such as Wilms tumour-associated antigen (WTAP).

  11. 01-01-2015 | Head and neck cancers | Book chapter | Article

    Head and neck tumors

    This chapter provides an overview of molecular testing for squamous mucosal lesions and salivary gland tumors. Laudadio J & Snow AN. In:  Molecular Oncology Testing for Solid Tumors . Edited by Idowu MO, Dumur CI, & Garrett CT. Springer International Publishing, 2015. doi:10.1007/978-3-319-16304-8_10

  12. 29-04-2015 | Head and neck cancers | ReviewPaper | Article

    Impact of weight loss in patients with head and neck carcinoma undergoing radiotherapy: is it an underestimated phenomenon? A radiation oncologist’s perspective

    Other high-risk patients were determined to have tumor or treatment factors (oral, midline oropharyngeal or nasopharyngeal tumor+chemoradiotherapy) that were predictive of the need for future tube feeding, in which the recommendation for gastrostomy placement was prophylactic. 18 In addition, Jack  et al. 18  addressed the appropriateness of prophylactic PEG insertion in patients undergoing surgical resection of intraoral/oropharyngeal tumors.

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