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Lomustine 

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  1. 05-10-2018 | Acute myeloid leukemia | News | Article

    Lomustine benefits older patients with favorable-, intermediate-risk AML

    Adding lomustine to standard chemotherapy with idarubicin and cytarabine significantly improves survival in fit older patients with favorable- or intermediate-risk acute myeloid leukemia, phase III trial data show.

  2. 21-11-2017 | Glioblastoma multiforme | News | Article

    Bevacizumab add-on fails to improve glioblastoma OS with lomustine

    Adding bevacizumab to lomustine does not prolong overall survival compared with lomustine alone in patients with progressive glioblastoma, but may delay disease progression, show phase III study data.

  3. 07-10-2017 | Glioblastoma multiforme | Article

    Randomized phase II trial comparing axitinib with the combination of axitinib and lomustine in patients with recurrent glioblastoma

    After the early promise shown by the small molecule tyrosine kinase inhibitor axitinib in patients with recurrent glioblastoma in a randomized phase II trial, this report details further investigation following amendment and continuation of the trial. Duerinck J et al. J Neurooncol 2017. doi:10.1007/s11060-017-2629-z

  4. 11-09-2017 | Glioblastoma multiforme | ESMO 2017 | Article
    ESMO 2017

    Regorafenib improves outcomes in relapsed glioblastoma patients

    The phase II REGOMA trial shows that patients with recurrent glioblastoma derive a significant overall survival and disease control benefit from treatment with regorafenib over lomustine.

  5. 27-08-2018 | Glioma | News | Article
    News in brief

    Bevacizumab strikes out in recurrent glioma

    . © 2018 Springer Healthcare part of the Springer Nature group See also: No event-free survival benefit with bevacizumab in pediatric high-grade glioma Bevacizumab add-on fails to improve glioblastoma OS with lomustine

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