Shen and co-authors point out that “MVI is also closely associated with tumor recurrence after liver transplantation for HCC,” and therefore suggest that further studies should investigate “whether pretransplant AVT affects the incidence of MVI in viral-related HCC.”

Hepatitis B virus infection is the leading cause of incident primary liver cancer and associated mortality worldwide, according to research published in JAMA Oncology .

A retrospective analysis has found a significantly higher incidence of hyperglycemia among breast cancer patients treated with alpelisib in standard care than on clinical trials.

In their chapter, Keane and Hong provide thoughtful discussion on the approaches to delivering and planning radiotherapy for the treatment of hepatocellular carcinoma and intrahepatic cholangiocarcinoma. Keane FK, Hong T. In:  Radiation therapy for gastrointestinal cancers. Edited by Hong T, Das P. Springer International Publishing AG, 2017. doi:10.1007/978-3-319-43115-4_10

Regorafenib was previously approved for the treatment of metastatic colorectal cancer and gastrointestinal stromal tumors that are no longer responsive to earlier treatment.

medwireNews : Supplementing standard systemic therapy with tumor treating fields (TTFields) prolongs the overall survival (OS) of previously treated patients with metastatic non-small-cell lung cancer (NSCLC), show phase 3 trial data.

Supplementing endocrine therapy with ribociclib significantly decreases the relapse risk in people with hormone receptor-positive, HER2-negative, early breast cancer.

Discussing the findings, they say that “[t]here are several potential risk factors for increased mortality of patients with pregnancy-associated cancer,” such as delays in time to diagnosis and cancer treatment initiation.

The current or recent use of progestagen-only contraceptives is associated with an increased risk for developing breast cancer, irrespective of the mode of delivery, suggests research published in PLOS Medicine .

The 15-year data from the ProtecT trial show low rates of prostate cancer-specific mortality among men with prostate-specific antigen-detected, localized disease regardless of whether they received active monitoring, prostatectomy, or radiotherapy.

People with cancer who have received COVID-19 vaccination are significantly less likely to experience persistent symptoms after recovery than unvaccinated individuals, irrespective of viral strain, suggest OnCovid data.

The 10-year data from the PRIME II trial suggest that radiotherapy after breast-conserving surgery can be omitted for women aged 65 years or older with low-risk, hormone receptor-positive early breast cancer.

Treatment with the novel oral selective estrogen receptor degrader camizestrant significantly improves progression-free survival versus fulvestrant in patients with pretreated, estrogen receptor-positive, HER2-negative advanced breast cancer, shows a phase 2 study.

The 3-year overall survival rate was 99.3%, with one death in a patient with a history of alcohol abuse and chronic hepatitis B and C disease who developed a second primary cancer of the liver.

Incidental irradiation of the sinoatrial node during lung cancer chemoradiotherapy may be associated with an increased risk for atrial fibrillation and death, research suggests.

Patients and methods Two cohorts of advanced and refractory cancer patients were seen in consecutive series for early phase trial enrolment consideration.

Discussant Sumanta Pal (City of Hope Comprehensive Cancer Center, Duarte, California, USA) commended the COSMIC-313 investigators for using “a contemporary control arm” and for taking “the bold move of comparing a triplet to a doublet.”