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50 search results for:

Liquid biopsy 

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  1. 18-03-2021 | Adis Journal Club | Article
    Targeted Oncology

    Liquid Biopsy for Prognosis and Treatment in Metastatic Colorectal Cancer: Circulating Tumor Cells vs Circulating Tumor DNA

    Because of its diagnostic, prognostic, and predictive value, liquid biopsy has been extensively studied also in metastatic colorectal cancer.

  2. 19-08-2020 | FDA | News | Article
    approvalsWatch

    FDA approves liquid biopsy NGS technology

    medwireNews : The US FDA has granted approval for the first liquid biopsy next-generation sequencing (NGS) assay, including as a specific companion diagnostic test for targeting use of osimertinib.

  3. 11-09-2020 | FDA | News | Article
    approvalsWatch

    FDA approves liquid biopsy test for somatic, germline mutations

    Patients who test negative with the liquid biopsy should be directed to routine biopsy and an approved tumour tissue test, the FDA advises.

  4. 22-07-2020 | Breast cancer | News | Article

    Liquid biopsy may predict early-stage TNBC recurrence

    The presence of circulating tumor DNA and circulating tumor cells in postsurgical samples is associated with relapse and poor outcomes in early-stage triple-negative breast cancer patients with an incomplete pathologic response to neoadjuvant chemotherapy, research suggests.

  5. 02-04-2019 | Non-small-cell lung cancer | Video | Article

    Researcher comment: Liquid biopsy noninferior to tissue biopsy for identifying genomic targets in metastatic NSCLC

    Researcher Vassiliki Papadimitrakopoulou describes the findings of the prospective NILE study evaluating the clinical utility of genotyping cell-free DNA in patients with a new diagnosis of metastatic non-small-cell lung cancer (3:21).

  6. 27-07-2017 | Colorectal cancer | Book chapter | Article

    Liquid biopsy in colorectal cancer

    Galvano A et al. In: Liquid Biopsy in Cancer Patients . Edited by Russo A, Giordano A, Rolfo C. Humana Press, Cham, 2017. doi: 10.1007/978-3-319-55661-1_13

  7. 27-07-2017 | Breast cancer | Book chapter | Article

    Liquid biopsy in breast cancer

    Incorvaia L et al. In: Liquid Biopsy in Cancer Patients . Edited by Russo A, Giordano A, Rolfo C. Humana Press, Cham, 2017. doi: 10.1007/978-3-319-55661-1_9

  8. 27-07-2017 | Non-small-cell lung cancer | Book chapter | Article

    Liquid biopsy in non-small cell lung cancer (NSCLC)

    Rolfo C et al. In: Liquid Biopsy in Cancer Patients . Edited by Russo A, Giordano A, Rolfo C. Humana Press, Cham, 2017. doi: 10.1007/978-3-319-55661-1_12

  9. 30-03-2017 | Diagnosis | News | Article
    News in brief

    Liquid biopsy-based method detects, locates cancer

    Researchers have developed a method that not only detects the presence of cancer from a blood sample, but also identifies the tissue of origin.

  10. 27-07-2017 | Hepatocellular carcinoma | Book chapter | Article

    Diagnostic and prognostic performance of liquid biopsy in hepatocellular carcinoma

    Labgaa I, Craig AJ, Villanueva A. In: Liquid Biopsy in Cancer Patients . Humana Press, Cham, 2017. Edited by Russo A, Giordano A, Rolfo C. doi: 10.1007/978-3-319-55661-1_14

  11. 14-04-2017 | Genitourinary cancers | Review | Article

    Liquid biopsy: A step forward towards precision medicine in urologic malignancies

    There is a growing trend towards exploring the use of a minimally invasive “liquid biopsy” to identify biomarkers in a number of cancers, including

  12. 13-09-2022 | ESMO 2022 | Conference coverage | Article

    Tepotinib–osimertinib combo shows early promise in advanced NSCLC

    A total of 425 patients with acquired resistance to first-line osimertinib were screened and MET amplification was centrally detected in 153 (36%) by fluorescent in situ hybridization (FISH) in tissue biopsy and/or next-generation sequencing (NGS) of liquid biopsy samples.

  13. 28-07-2022 | Liquid biopsy | News | Article

    ctDNA analysis can detect KRAS G12C mutations in people with cancer

    Focusing on the 129 patients with KRAS G12C-positive cancer who had both ctDNA and tissue biopsy results available, the researchers found a high concordance between the modalities for cases where the liquid and tissue biopsies were performed within 6 months (time synchronous), but not for those where the tests were done more than 6 months apart (time asynchronous).

  14. 13-06-2022 | ASCO 2022 | Conference coverage | Article

    ctDNA identifies patients before late HR-positive breast cancer recurrence

    “This will inform future studies of liquid biopsy to personalize treatment and prevent or delay late recurrence of early-stage breast cancer.”

  15. 09-06-2022 | ASCO 2022 | Conference coverage | Article

    Biomarker may predict neoadjuvant treatment response in bladder cancer

    Methylation levels of cell-free DNA in pretreatment plasma samples from people with muscle-invasive bladder cancer may predict pathologic response to neoadjuvant chemotherapy, suggests an analysis of prospective SWOG S1314 data.

  16. 11-04-2022 | ALK-mutated NSCLC | Interview | Article

    Pathologic testing for ALK and ROS1 aberrations in NSCLC

    If the patient has very low tumor content in the biopsy, so we will use liquid biopsy.

  17. 23-03-2022 | Non-small-cell lung cancer | News | Article

    Post-treatment ctDNA predicts poor outcomes in early-stage NSCLC

    The results of sequencing were then used to design patient-specific RaDaR™ next-generation sequencing liquid biopsy assays that target 48 tumor-specific variants unique to each patient.

  18. 14-12-2021 | SABCS 2021 | Conference coverage | Article

    PADA-1 shows clinical utility of blood ESR1 mutation monitoring

    Women with hormone receptor-positive, HER2-negative metastatic breast cancer benefit from switching from an aromatase inhibitor to fulvestrant in palbociclib combination therapy when an ESR1 mutation is detected without disease progression, phase 3 PADA-1 trial data show.

  19. play
    28-09-2021 | ESMO 2021 | Conference coverage | Video

    ctDNA analysis may help to personalize metastatic urothelial carcinoma treatments

    Guru Sonpavde outlines the findings of their immunotherapy study supporting a potential role for longitudinal ctDNA profiling to identify suitable therapies for people with metastatic urothelial cancer. This independent video interview was supported by an educational grant from Pfizer and Merck Healthcare KGaA, Darmstadt, Germany

  20. 13-09-2021 | WCLC 2021 | Conference coverage | Article

    ​​​​​​​Pretreatment ctDNA levels may predict survival in neoadjuvant-treated NSCLC patients

    Assessing circulating tumor DNA levels prior to initiating neoadjuvant chemoimmunotherapy for locally advanced non-small-cell lung cancer could help to identify patients likely to derive long-term benefit from treatment, suggest exploratory data.

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