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Human papillomavirus 

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  1. 15-08-2017 | Head and neck cancers | Article

    The role of human papillomavirus on the prognosis and treatment of oropharyngeal carcinoma

    The authors review the impact of human papillomavirus on the prognosis of oropharyngeal carcinoma at diagnosis and disease progression, as well as potential factors mediating improved prognosis. Fung N, Faraji F, Kang H & Fakhry C. Cancer Metastasis Rev 2017; 3: 449-461. doi:10.1007/s10555-017-9686-9

  2. 27-07-2017 | Head and neck cancers | Article

    Prognostic implications of human papillomavirus status for patients with non-oropharyngeal head and neck squamous cell carcinomas

    This retrospective, observational, large cohort study compares overall survival of patients with human papilloma virus-positive and negative non-oropharyngeal head and neck squamous cell carcinomas. Ko HC, Harari PM, Sacotte RM et al. J Cancer Res Clin Oncol 2017. doi:10.1007/s00432-017-2481-8

  3. 13-06-2013 | Head and neck cancers | Article

    Molecular analyses of unselected head and neck cancer cases demonstrates that human papillomavirus transcriptional activity is positively associated with survival and prognosis

    Data from this small study suggest that HPV16 oncogenic transcriptional activity within head and neck squamous cell carcinoma tumors is associated with improved patient survival and better prognosis in a German population. Masterson L et al. BMC Cancer 2016; 16: 367. doi:10.1186/s12885-016-2398-7

  4. 05-10-2018 | Human papillomavirus | News | Article

    HPV-16 vaccine may boost nivolumab efficacy in HPV-16–positive cancer

    The efficacy of programmed cell death protein 1 inhibition with nivolumab may be amplified by vaccination against human papillomavirus-16 in patients with incurable HPV-16–positive cancer, phase II study data suggest.

  5. 17-08-2018 | Cervical cancer | News | Article

    Catch-up HPV vaccination supported in older adolescence

    US researchers have found evidence to support catch-up vaccination against the human papillomavirus in women given their first dose in older adolescence.

  6. 15-05-2018 | Head and neck cancers | News | Article

    HPV positivity may improve survival in some nonoropharyngeal head and neck cancers

    Human papillomavirus positivity is associated with improved survival in patients with head and neck cancer at four of six subsites in the upper aerodigestive tract, US study findings indicate.

  7. 10-05-2018 | Cervical cancer | News | Article

    HPV vaccine reassurance for younger women

    Prophylactic vaccination against human papillomavirus is highly effective in preventing cervical precancer in adolescent girls and young women, and is not associated with an elevated risk for serious adverse events, finds a Cochrane Library review.

  8. 15-02-2018 | Human papillomavirus | News | Article
    News in brief

    Educational gap exposed on HPV link to head and neck cancer

    A survey of New York state medical students suggests many are unaware of the link between human papillomavirus infection and the risk for head and neck cancer.

  9. 15-10-2018 | FDA | News | Article
    approvalsWatch

    HPV vaccination age expanded in the USA

    medwireNews : The US FDA has agreed to expand the age range for use of the recombinant human papillomavirus (HPV) 9-valent vaccine to include women and men aged 27 to 45 years This particular vaccine was approved in 2014 for the prevention of cervical cancer associated with HPV infection in patients aged 9 to 26 years.

  10. 01-12-2017 | Pancreatic cancer | News | Article

    In other news

    This roundup covers three articles published in  JAMA Oncology , with subjects including genetic predictors of resected pancreatic ductal adenocarcinoma outcomes, the efficacy of ipilimumab in cervical cancer associated human papillomavirus, and the effect of the US Affordable Care Act on cancer screening.

  11. 06-06-2017 | Human papillomavirus | Conference coverage | Article
    ASCO 2017

    HPV vaccination ‘tremendous potential’ for prevention of oral HPV infection

    Routine vaccination against human papillomavirus has “tremendous potential” for reducing the risk of oral HPV infection and associated malignancy, suggests research presented at the 2017 American Society of Clinical Oncology annual meeting, held in Chicago, Illinois, USA.

  12. 24-08-2017 | Nasopharyngeal cancer | News | Article

    EBV DNA positivity may signify asymptomatic nasopharyngeal carcinoma

    “Like cervical cytologic testing or testing for human papillomavirus in the cervix for early detection of cervical cancer, plasma EBV DNA screening may profoundly change the natural history of nasopharyngeal carcinoma,” Ambinder concludes.

  13. 04-11-2016 | Gynecologic cancers | Article

    Perspectives for therapeutic HPV vaccine development

    This review discusses various therapeutic human papillomavirus (HPV) vaccines in development for the treatment of existing HPV infections and HPV-associated diseases, including HPV-associated cancers. Yang A et al. J Biomed Sci 2016; 23: 75. doi:10.1186/s12929-016-0293-9

  14. 29-08-2017 | Head and neck cancers | Article

    Biomarker driven treatment of head and neck squamous cell cancer

    Eze et al. review p16 overexpression as a surrogate biomarker in human papillomavirus-associated head and neck cancer and plasma Epstein Barr virus DNA as a biomarker in nasopharyngeal carcinoma. Eze N, Lo YC & Burtness B. Cancers Head Neck 2017; 2: 6. doi: 10.1186/s41199-017-0025-1

  15. 11-07-2017 | Cervical cancer | News | Article

    HPV testing increases high-grade CIN detection following abnormal cytology

    Human papillomavirus testing after abnormal cytology improves detection of high-grade cervical intraepithelial neoplasia lesions but with associated increases in biopsy and loop electrosurgical excision procedure rates, researchers report.

  16. 02-06-2018 | Head and neck cancers | ASCO 2018 | Article

    Disparity by sex may exist for head and neck cancer treatment, outcomes in USA

    For instance, a smaller proportion of women than men had oropharyngeal cancers (38 vs 55%) – these are often associated with human papillomavirus (HPV) positivity, which in turn is generally associated with better prognosis and outcomes.

  17. 11-04-2017 | Cervical cancer | News | Article

    HPV vaccine exposure during pregnancy not linked to adverse outcomes

    Women who inadvertently receive the quadrivalent human papillomavirus vaccine during pregnancy are not at increased risk for adverse pregnancy outcomes over women with no such exposure, results of a Danish nationwide cohort study show.

  18. 29-01-2018 | Cervical cancer | News | Article

    Excess bodyweight may hinder cervical precancer diagnosis and increase cancer risk

    The analysis included 944,227 women aged 30–64 years who underwent screening by cytology and human papillomavirus (HPV) DNA co-testing at Kaiser Permanente Northern California in Oakland, USA, between 2003 and 2015.

  19. 03-06-2016 | Head and neck cancers | Article

    Genomic insights into head and neck cancer

    This review summarizes and highlights potential therapeutic opportunities in human papillomavirus (HPV-) and HPV+ head and neck squamous cell carcinoma based on the analysis of high throughput data published by The Cancer Genome Atlas network and others. Beck TN & Golemis EA. Cancers Head Neck 2016;1:1. doi:10.1186/s41199-016-0003-z

  20. 11-01-2017 | Oropharyngeal and hypopharyngeal cancers | News | Article

    HPV-negative OPSCC survival comparable with upfront surgery and CRT

    A US research team has found no significant difference in overall survival between patients with human papillomavirus-negative early-stage oropharyngeal squamous cell carcinoma who received upfront surgery and those given concurrent chemoradiation.

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