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Hepatoblastoma 

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  1. 28-06-2018 | Ototoxicity | News | Article

    Sodium thiosulfate protects against hearing loss in cisplatin-treated children with hepatoblastoma

    The administration of sodium thiosulfate after cisplatin reduces the incidence of hearing loss in children with standard-risk hepatoblastoma, according to an international, randomized trial.

    Published in:
    N Engl J Med 2018; 378 : 2376–2385
  2. 12-12-2016 | Ototoxicity | News | Article
    Editor's pick

    Sodium thiosulfate otoprotective in cisplatin-treated pediatric cancer patients

    “The potential clinical effect of these findings is to offer, at a very affordable cost, a possible decrease in a toxicity that has too often been regarded as a price to pay for survival, especially for patients with germ cell tumours, hepatoblastoma, neuroblastoma, osteosarcoma, and medulloblastoma, in which cisplatin is part of the standard of care,” Eric Bouffet (The Hospital for Sick Children, Toronto, Ontario, Canada) writes in an accompanying commentary .

    Published in:
    Lancet Oncol 2016; Advance online publication
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