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19 search results for:

Ductal carcinoma in situ 

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  1. 28-10-2017 | Ductal carcinoma in situ | Article

    Clinical risk score to predict likelihood of recurrence after ductal carcinoma in situ treated with breast-conserving surgery

    Punglia RS et al. Breast Cancer Res Treat 2017. doi:10.1007/s10549-017-4553-5

  2. 06-11-2017 | Ductal carcinoma in situ | Article

    Detection Rates of Ductal Carcinoma in Situ with Biennial Digital Mammography Screening: Radiologic Findings Support Pathologic Model of Tumor Progression

    Radiology  2018; 286(2): 424-432. doi: 10.1148/radiol.2017170673 Please follow the link below to view this article in full on a third party website.

  3. 06-10-2022 | Breast cancer | News | Article

    Meta-analysis shows link between margin involvement and poor breast cancer outcomes

    Involved or close pathologic margins after breast conserving surgery are associated with an increased risk for distant recurrence and mortality in women with early-stage invasive breast cancer, indicates a meta-analysis.

    Author:
    Shreeya Nanda
    Published in:
    BMJ 2022; 378 : e070346
  4. 04-10-2021 | Breast cancer | News | Article

    Toxicity Index, PRO data shed light on early endocrine therapy discontinuations

    All of the women included in the study were postmenopausal with ductal carcinoma in situ that had been treated with breast-conserving therapy.

    Author:
    Laura Cowen
    Published in:
    J Clin Oncol 2021; doi:10.1200/JCO.21.00910
  5. 24-12-2020 | Breast cancer | News | Article

    HRQoL effects of breast cancer prognosis, treatment predict mortality risk

    The health-related quality of life of patients with ductal carcinoma in situ or invasive breast cancer is impaired by their prognosis and treatment, and measuring the extent of impairment could help predict mortality risk, research suggests.

    Author:
    Hannah Kitt
    Published in:
    Cancer 2020; doi:10.1002/cncr.33348
  6. play
    11-12-2020 | SABCS 2020 | Conference coverage | Video

    Comparable outcomes, different toxicities with anastrozole, tamoxifen in DCIS

    Ivana Sestak puts the long-term results of the IBIS-II trial in the context of the NSABP B-35 study, both of which compared anastrozole with tamoxifen for breast cancer prevention in postmenopausal women with HR-positive ductal carcinoma in situ.

  7. 14-12-2020 | SABCS 2020 | Conference coverage | Article

    ​​​​​​​IBIS-II update shows no difference in anastrozole, tamoxifen efficacy in DCIS

    Long-term results from the IBIS-II trial show a comparable risk for breast cancer recurrence with anastrozole and tamoxifen among postmenopausal women with hormone receptor-positive ductal carcinoma in situ.

    Author:
    Hannah Kitt
    Published in:
    SABCS 2020: 8–11 December
  8. 17-03-2021 | Breast cancer | News | Article

    Neoadjuvant treatment choice impacts invasive ductal carcinoma survival

    Neoadjuvant chemotherapy may lead to better survival than neoadjuvant endocrine therapy in women with hormone receptor-positive, HER2-negative invasive ductal carcinoma of the breast, show registry data from Taiwan.

    Author:
    Laura Cowen
    Published in:
    JAMA Netw Open 2021; 4 : e211785
  9. 27-07-2020 | Breast cancer | News | Article
    News in brief

    Guidance proposed for managing breast cancer during COVID-19

    A stage- and subtype-specific approach for the management of breast cancer during the COVID-19 outbreak has been published in JCO Oncology Practice .

    Author:
    Shreeya Nanda
    Published in:
    JCO Oncol Pract 2020; doi:10.1200/OP.20.00364
  10. 20-08-2018 | Ductal carcinoma in situ | News | Article

    Adjuvant radiotherapy may improve DCIS outcomes

    Canadian researchers have found that the use of radiotherapy after surgery for ductal carcinoma in situ leads to an improvement in breast cancer-specific survival, possibly due to its systemic effects.

    Published in:
    JAMA Network Open 2018; 1 : e181100
  11. 17-10-2017 | Breast cancer | Article

    The importance of early detection of calcifications associated with breast cancer in screening

    Mordang JJ et al. Breast Cancer Res Treat 2017. doi:10.1007/s10549-017-4527-7

  12. 07-04-2017 | Ductal carcinoma in situ | News | Article

    Radiotherapy boost reduces DCIS recurrence risk

    A radiotherapy boost to the tumor bed following whole-breast radiotherapy for ductal carcinoma in situ significantly reduces the risk for ipsilateral breast tumor recurrence, pooled study data show.

    Published in:
    JAMA Oncol 2017; Advance online publication
  13. 09-11-2017 | Breast cancer | Article

    Reproductive risk factor associations with lobular and ductal carcinoma in the Carolina Breast Cancer Study

    Williams L.A et al. Cancer Causes Control 2018; 29: 25. doi:10.1007/s10552-017-0977-9

  14. 16-11-2016 | Triple-negative breast cancer | Article

    Triple-negative breast cancer: the importance of molecular and histologic subtyping, and recognition of low-grade variants

    Low-grade TN breast neoplasia family It is currently perceived that breast cancer evolution can be stratified into two main pathways according to ER pathway activation. 101 ER-positive breast neoplasms encompass a spectrum of pre-invasive (columnar cell lesions, atypical ductal hyperplasia, lobular neoplasia, and low-grade ductal carcinoma in situ ) and invasive lesions (invasive tubular, lobular, and low-grade ductal carcinomas), and progression from low- to high-grade lesions may take place. 22 Owing to their frequent coexistence and similar pattern of genetic alterations (e.g., PIK3CA mutations and deletions of 16q and gains of 1q 23,101 ), low-grade ER-positive non-obligate precursors and invasive carcinomas have been grouped together under the term ‘low-grade breast neoplasia family’. 101 Akin to the low-grade ER-positive breast neoplasia family, a subset of related low-grade neoplastic entities can also be distinguished among the TN lesions of the breast.

    Author:
    Fresia Pareja, Felipe C Geyer, Caterina Marchiò, Kathleen A Burke, Britta Weigelt, Jorge S Reis-Filho
  15. 02-03-2017 | Liquid biopsy | Review | Article

    Integrating liquid biopsies into the management of cancer

    Notably, however, Wang and colleagues 8 analysed DNA in saliva for potential tumour biomarkers in 93 patients with head and neck squamous-cell carcinoma (HNSCC).

    Author:
    Giulia Siravegna, Silvia Marsoni, Salvatore Siena, Alberto Bardelli
  16. 17-05-2016 | Triple-negative breast cancer | Article

    Triple-negative breast cancer: Challenges and opportunities of a heterogeneous disease

    Immunohistochemical definition of TNBC The diagnosis of TNBC depends on the accurate assessment of ER and PgR protein expression levels by immunohistochemistry (IHC), and of HER2 by IHC and/or fluorescence  in situ  hybridization (FISH).

    Author:
    Giampaolo Bianchini, Justin M. Balko, Ingrid A. Mayer, Melinda E. Sanders, Luca Gianni
  17. 27-01-2015 | Breast cancer | Article

    Current management of lesions associated with an increased risk of breast cancer

    In addition to ADH and ALH, there are two forms of breast carcinoma  in situ  that are recognized to increase the risk of later invasive breast carcinoma development: lobular carcinoma  in situ  (LCIS) and ductal carcinoma  in situ  (DCIS).

    Author:
    Monica Morrow, Stuart J. Schnitt, Larry Norton
  18. 07-04-2015 | Surgery | Article

    Surgical issues in patients with breast cancer receiving neoadjuvant chemotherapy

    Additionally, some definitions of pCR include patients with residual ductal carcinoma in situ (DCIS), which can preclude BCS.

    Author:
    Tari A. King, Monica Morrow
  19. 25-07-2018 | Pregnancy | News | Article

    Assisted reproduction linked to increased breast and ovarian cancer risk

    Women who undergo assisted reproduction may be at increased risk for in situ breast cancer, and invasive and borderline ovarian tumors, show results of a large, population-based study.

    Published in:
    BMJ 2018; 362 : k2644
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