We found that prostate-specific membrane antigen positron emission tomography/computed tomography is likely to be more costly than computed tomography plus a whole-body bone scan or computed tomography alone in Australia; however, it is still likely to be considered cost effective for patients with newly diagnosed, intermediate-risk or high-risk primary prostate cancer.

But they “unexpectedly encountered 2 grade 5 pneumonitis events that had not been reported at that time” and therefore “decided to closely review the records and CT [computed tomography] findings of a subset of patients treated with EV to determine the incidence, severity, and clinical outcomes of EV-related pneumonitis.”

Minimizing irradiation by either switching from computed tomography to magnetic resonance imaging scans or by reducing scan frequency is not detrimental to stage I seminoma outcomes, show data from the UK-based TRISST trial.

The majority (n=916; 79.7%) presented with incidental nodules (≥6 mm) with the remainder (n=234; 20.3%) having chest computed tomography screen-detected nodules (Lung Imaging Reporting and Data System category 4).

An analysis of computed tomography scans from people with thoracic malignancies shows that approximately one in 11 people develop axillary lymphadenopathy following mRNA-based COVID-19 vaccination.

The US Preventive Services Task Force has updated its recommendations for lung cancer screening with low-dose computed tomography among current and former smokers.

The Taiwan Lung Cancer Screening in Never-Smoker Trial suggests that low-dose computed tomography screening may help to detect early-stage disease in never smokers at high risk for developing lung cancer.

medwireNews : Postprostatectomy salvage radiotherapy guided by 18 F-fluciclovine-positron emission tomography (PET)–computed tomography (CT) is associated with improved outcomes relative to that guided by conventional imaging, research suggests.

They add: “The toxicity was modest, suggesting that concerns about toxicity from twice-daily thoracic radiotherapy might be unjustified when using modern radiotherapy techniques and limiting radiotherapy fields to PET-CT [positron emission tomography-computed tomography] positive lesions.”

Use of positron emission tomography–computed tomography before diagnosis is associated with increased receipt of stage-appropriate treatment and decreased mortality among veterans with non-small-cell lung cancer, research suggests.

And a chest computed tomography (CT) scan showed the presence of bilateral ground glass opacities signifying COVID-19.

The researchers report a significant correlation between severe clinical events and receipt of anticancer therapy in the 14 days prior to the COVID-19 diagnosis, with patchy consolidation on computed tomography (CT) at admission the other significant factor.

COVID-19 was diagnosed in 12 patients, primarily on the basis of a positive computed tomography result in 10 patients, with just four testing positive on the SARS-CoV2 real-time quantitative polymerase chain reaction assay.

Patients with cancer were significantly older than those without cancer, at an average age of 63.1 versus 48.7 years, and were significantly more likely to have a history of smoking (22.2 vs 6.8%), severe abnormalities on baseline computed tomography (CT; 94.4 vs 70.8%), and polypnea at presentation (47.1 vs 23.5%).

Individuals at high risk for developing lung cancer benefit from periodic screening with low-dose computed tomography, indicate the 10-year results from the NELSON trial.

medwireNews : 68 Ga-prostate-specific membrane antigen (PSMA)-11 should be the “tracer of choice” for positron emission tomography–computed tomography (PET–CT) to detect the postoperative biochemical recurrence of prostate cancer, say researchers who conducted a comparative imaging trial.

After 6 days, the patient was additionally treated with azithromycin, methylprednisolone, and enoxaparin, and 4 days later most skin lesions had resolved, and the patient’s chest computed tomography results were normal.

Positron-emission tomography using the novel prostate-specific membrane antigen targeted 18 F-DCFPyL tracer shows “excellent diagnostic performance” in men with biochemically recurrent prostate cancer, researchers report.

Combining low-dose computed tomography with a blood microRNA test can help establish the most appropriate screening frequency among heavy smokers at risk for lung cancer, study data show.

WATCH | Ugo Pastorino discusses the bioMILD study, which investigates a lung cancer screening program that supplements low-dose computed tomography with a blood microRNA assay (3:09).