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8 search results for:

Bosutinib 

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  1. 21-12-2017 | FDA | News | Article
    approvalsWatch

    FDA approvals announced for advanced RCC, CML

    . --- Bosutinib has been given accelerated approval for first-line use in patients with CML–CP who test positive for the Philadelphia chromosome.

  2. 02-02-2018 | Chronic myeloid leukemia | Highlight | Teaser
    Expert opinion

    Discontinuing tyrosine kinase inhibitors in chronic myeloid leukemia

    Tyrosine kinase inhibitor (TKI) treatment of chronic myeloid leukemia (CML) can result in prolonged and deep responses in many patients. In such cases, can TKIs be safely discontinued to avoid adverse side effects and costs? Etab Atallah (Medical College of Wisconsin, USA) discusses the current issues surrounding TKI discontinuation in CML.

  3. 18-10-2016 | Bcr-Abl tyrosine kinase inhibitors | ReviewPaper | Article

    Tyrosine kinase inhibitors in chronic myeloid leukaemia: which, when, for whom?

    Bosutinib.  

    Author:
    Gianantonio Rosti, Fausto Castagnetti, Gabriele Gugliotta, Michele Baccarani
  4. 03-06-2016 | Chronic myeloid leukemia | Article

    European LeukemiaNet recommendations for the management and avoidance of adverse events of treatment in chronic myeloid leukaemia

    For dasatinib, nilotinib and bosutinib, caution is necessary, as reports on cardiac toxicity may arise.

    Author:
    J L Steegmann, M Baccarani, M Breccia, L F Casado, V García-Gutiérrez, A Hochhaus, D-W Kim, T D Kim, H J Khoury, P Le Coutre, J Mayer, D Milojkovic, K Porkka, D Rea, G Rosti, S Saussele, R Hehlmann, R E Clark
  5. 15-11-2016 | Acute lymphoblastic leukemia | Book chapter | Article

    Therapeutic management of acute lymphoblastic leukemia

    First- (imatinib) and second-generation tyrosine kinase inhibitors (TKIs; nilotinib, dasatinib, bosutinib, and ponatinib) are available and their optimal use in BCR-ABL + ALL is under intensive investigation.

    Author:
    Karsten Spiekermann
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