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Adjuvant therapy 

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  1. 26-04-2022 | Breast cancer | News | Article
    guidelinesWatch

    ASCO issues updated guideline on biomarker assays for early breast cancer adjuvant therapy

    medwireNews : ASCO has updated its recommendations for using biomarker assays to guide adjuvant therapy decisions in people with early-stage breast cancer.

  2. 23-09-2021 | Melanoma | Adis Journal Club | Article
    Targeted Oncology

    The Status of Adjuvant and Neoadjuvant Melanoma Therapy, New Developments and Upcoming Challenges

    Interferon-α has long been the only approved drug for adjuvant melanoma therapy, despite an unclear survival benefit.

  3. 29-07-2021 | Breast cancer | News | Article

    Extending adjuvant AI therapy by 2 years sufficient in postmenopausal breast cancer

    The phase 3 SALSA trial has demonstrated no benefit of extending aromatase inhibitor therapy by 5 years versus 2 years in postmenopausal women with hormone receptor-positive breast cancer who have already received 5 years of adjuvant endocrine therapy.

  4. 24-09-2018 | Breast cancer | Article

    Progress in adjuvant systemic therapy for breast cancer

    Pondé NF, Zardavas D, Piccart M. Nat Rev Clin Oncol  2018. doi:10.1038/s41571-018-0089-9

  5. 04-06-2018 | Breast cancer | Article

    Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer

    Francis PA et al. N Engl J Med 2018. doi:10.1056/NEJMoa1803164

  6. 01-08-2017 | Pancreatic cancer | Book chapter | Article

    Adjuvant Chemoradiation Therapy for Pancreatic Cancer

    This chapter critically examines published data on adjuvant chemoradiation therapy for pancreatic cancer, and assesses the needs for future trials to find the optimal treatment and improve patient outcomes. Kaiser A et al. In: Pancreatic Cancer. Edited by Neoptolemos JP et al. Springer International Publishing, 2017. doi: 10.1007/978-1-4939-6631-8

  7. 04-01-2019 | Supportive care | Article

    Cognitive effects of adjuvant endocrine therapy in older women treated for early-stage breast cancer: a 1-year longitudinal study

    Underwood EA et al. Support Care Cancer 2019; 27: 3035. doi:10.1007/s00520-018-4603-5

  8. 12-01-2018 | FDA | News | Article
    approvalsWatch

    Pertuzumab approved as adjuvant therapy for HER2-positive breast cancer

    medwireNews : The US FDA has given the go-ahead for the addition of pertuzumab to adjuvant trastuzumab and chemotherapy for patients with early-stage, human epidermal growth factor receptor 2 (HER2)-positive breast cancer at high risk for recurrence after resection.

  9. 27-06-2018 | Targeted therapy | Article

    Selection of Optimal Adjuvant Chemotherapy and Targeted Therapy for Early Breast Cancer: ASCO Clinical Practice Guideline Focused Update

    Denduluri N et al. J Clin Oncol  2018; JCO2018788604. doi:10.1200/JCO.2018.78.8604

  10. 24-07-2017 | FDA | News | Article
    approvalsWatch

    Extended neratinib adjuvant therapy approved for HER2-positive breast cancer

    medwireNews : The dual HER2 and EGFR kinase inhibitor neratinib has received US FDA approval for use in patients with early-stage HER2-positive breast cancer who have previously received adjuvant therapy including trastuzumab.

  11. 09-10-2017 | Breast cancer | Article

    Patterns of axillary evaluation in older patients with breast cancer and associations with adjuvant therapy receipt

    Dominici LS, Sineshaw HM, Jemal A et al. Breast Cancer Res Treat 2017. doi:10.1007/s10549-017-4528-6

  12. 01-01-2018 | Breast cancer | Article

    Optimal Duration of Extended Adjuvant Endocrine Therapy for Early Breast Cancer; Results of the IDEAL Trial (BOOG 2006-05)

    Blok EJ et al.  J Natl Cancer Inst  2018; 110(1). doi:10.1093/jnci/djx134

  13. 05-09-2017 | Pancreatic cancer | Article

    Redefining the Positive Margin in Pancreatic Cancer: Impact on Patterns of Failure, Long-Term Survival and Adjuvant Therapy

    This pathology study highlights the clinical significance of the posterior surgical resection margins and the lack of significance of other resection margins in pancreatic ductal adenocarcinoma. Osipov A et al. Ann Surg Oncol 2017; doi:org/10.1245/s10434-017-6076-z

  14. 25-11-2022 | Breast cancer | News | Article

    GIM2 defines ‘optimal’ high-risk early breast cancer adjuvant chemotherapy

    End-of-study findings from the GIM2 trial indicate that adjuvant anthracyclines plus taxane chemotherapy for high-risk early breast cancer should be given in a dose-dense regimen and should not include fluorouracil.

  15. 22-11-2016 | Breast cancer | Article

    Adjuvant chemotherapy and HER-2-directed therapy for early-stage breast cancer in the elderly

    Assuming that capecitabine does not have a detrimental effect on DFS, this study would suggest that adjuvant poly-chemotherapy does in fact have an adjuvant impact in elderly patients with early-stage breast cancer.

  16. 06-06-2023 | Non-small-cell lung cancer | Conference coverage | Article
    ASCO 2023

    ADAURA demonstrates OS gain with adjuvant osimertinib in early-stage NSCLC

    Adjuvant treatment with osimertinib significantly prolongs overall survival relative to placebo in people with EGFR -mutated, early-stage non-small-cell lung cancer, show trial results.

  17. 10-10-2022 | Breast cancer | News | Article

    Lower pCR rate highlighted for male breast cancer after neoadjuvant chemotherapy

    Men are less likely than women to achieve a pathologic complete response to neoadjuvant chemotherapy for invasive, nonmetastatic breast cancer, US researchers report.

  18. 05-06-2023 | Breast cancer | Conference coverage | Article
    ASCO 2023

    Adjuvant ribociclib reduces recurrence risk in early breast cancer

    Supplementing endocrine therapy with ribociclib significantly decreases the relapse risk in people with hormone receptor-positive, HER2-negative, early breast cancer.

  19. 15-06-2023 | Non-small-cell lung cancer | News | Article
    ASCO 2023

    Interim KEYNOTE-671 findings support perioperative pembrolizumab for resectable NSCLC

    After completing neoadjuvant therapy, 82.1% of the 397 patients in the pembrolizumab arm underwent planned surgery, as did 79.4% of the 400 patients given placebo.

  20. 04-11-2015 | Non-melanoma skin cancer | Case report | Article

    Case report: Imiquimod 5% as adjuvant therapy for incompletely excised infiltrative nodular basal cell carcinoma and dermoscopy to monitor treatment response

    Roldán-Marín R, Toussaint-Caire S. Dermatol Ther (Heidelb) 2015;5:265–272. doi:10.1007/s13555-015-0088-z

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