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Thomas Powles

Barts Cancer Center, Barts & The London School of Medicine & Dentistry, Queen Mary University of London, London, UK

Thomas Powles, MD, MRCP, MBBS, is a Professor of Genitourinary Oncology and Director of Barts Centre in London, UK. He trained in medical oncology at Imperial College London, completed post-graduate training in oncology in 2005, and received an MD from the University of London in 2006, with a thesis on mechanisms of resistance to therapy in urological cancers.

Professor Powles is the lead for solid tumor research at Barts Cancer Institute, and the PI of a spectrum of clinical studies from Phase I-III, including biomarker, novel targeted and immune therapies studies.

He has written over 300 peer-reviewed publications including work in all the major journals. Professor Powles participates in and leads a number guidelines committees.

Disclosures:

  • Consultancy/honorarium: AstraZeneca, BMS, Exelixis, Incyte, Ipsen, Merck, MSD, Novartis, Pfizer, Seattle Genetics, Merck Serono (EMD in US), Astellas, Johnson & Johnson, Eisai, Roche
  • Grant/funding to institution: AstraZeneca, Roche, BMS, Exelixis, Ipsen Merck MSD, Novartis, Pfizer, Seattle Genetics, Merck Serono (EMD in US), Astellas , Johnson & Johnson , Eisai
  • Travel/accommodation: Roche, Pfizer, MSD, AstraZeneca, Ipsen
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Latest contributions from Thomas Powles

Thomas Powles

12-02-2021 | ASCO GU 2021 | Conference coverage | Video

EV-301: Enfortumab vedotin boosts advanced urothelial cancer survival

Thomas Powles outlines the primary results of the phase 3 EV-301 trial comparing enfortumab vedotin with chemotherapy in patients who have received prior treatment for locally advanced or metastatic urothelial carcinoma (4:37).

Key results on urothelial carcinoma presented at ASCO GU 2021

20-01-2021 | Urothelial cancer | Video

Key results on urothelial carcinoma presented at ASCO GU 2021

Fredrik Liedberg and Thomas Powles discuss their thoughts on the game-changing results on metastatic urothelial carcinoma presented at ASCO GU (15:35).

This activity is supported by an educational grant from Pfizer and Merck Healthcare KGaA, Darmstadt, Germany.

17-12-2020 | Urothelial cancer | News

ctDNA status linked to adjuvant atezolizumab benefit for muscle-invasive UC

Circulating tumor DNA status may help identify muscle-invasive urothelial cancer patients who will benefit from adjuvant treatment with atezolizumab, suggests an exploratory analysis of the IMvigor010 participants.

Thomas Powles

19-09-2020 | ESMO 2020 | Conference coverage | Video

JAVELIN Bladder 100: Identifying biomarkers for maintenance avelumab

Thomas Powles discusses the key findings from the biomarker analyses of the JAVELIN Bladder 100 study of maintenance avelumab in patients with advanced urothelial cancer.

This independent video interview was supported by an educational grant from Pfizer and Merck Healthcare KGaA, Darmstadt, Germany