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Renal cell carcinoma

Treatment

15-11-2019 | Renal cell carcinoma | At a glance | Article

At a glance: The IMmotion RCC trials

A quick-reference guide to the IMmotion trials evaluating the anti-PD-L1 agent atezolizumab for the treatment of renal cell carcinoma.

31-10-2019 | Renal cell carcinoma | At a glance | Article

At a glance: The JAVELIN RCC trials

A quick-access guide to the JAVELIN trials of the anti-PD-L1 agent avelumab in the renal cell carcinoma setting.

07-10-2019 | Renal cell carcinoma | Video | Article

Researcher comment: A novel CXCR4 inhibitor for RCC and a novel immunotherapy endpoint

David McDermott talks through his renal cell carcinoma research exploring the use of a novel oral CXCR4 inhibitor and treatment-free survival as an alternative endpoint for immunotherapy trials (4:03).

This independent video interview was supported by an educational grant from Pfizer and Merck KGaA

01-10-2019 | Renal cell carcinoma | Video | Article

Researcher comment: JAVELIN Renal 101 – combination approach for advanced RCC patients without upfront cytoreductive nephrectomy

Laurence Albiges discusses a JAVELIN Renal 101 subgroup analysis indicating that avelumab plus axitinib achieves tumor reduction in patients with metastatic renal cell carcinoma (2:30).

This independent video interview was supported by an educational grant from Pfizer and Merck KGaA

30-09-2019 | Renal cell carcinoma | Video | Article

Researcher comment: TITAN-RCC findings show efficacy of tailored immunotherapy approach

Marc-Oliver Grimm talks through the results of the tailored nivolumab plus boost ipilimumab approach used in the TITAN-RCC study (3:38).

This independent video interview was supported by an educational grant from Pfizer and Merck KGaA

30-09-2019 | Renal cell carcinoma | Video | Article

Expert comment: RCC immunotherapy – biomarker round-up

Guillermo de Velasco discusses four posters presented at the ESMO Congress 2019 focusing on biomarker analyses of the ADAPTeR, JAVELIN Renal 101 and NIVOREN GETUG-AFU 26 trials (6:07).

This independent video interview was supported by an educational grant from Pfizer and Merck KGaA

Screening, diagnosis and staging

14-04-2016 | Staging | Book chapter | Article

Diagnosis and management of hereditary renal cell cancer

Hereditary renal cell carcinoma (RCC) is the umbrella term for about a dozen different conditions. This chapter provides an overview of the main hereditary RCC syndromes and discusses management options.

Menko FH & Maher ER. In: Rare Hereditary Cancers. Edited by Pichert G, Jacobs C. Springer International Publishing, 2016. doi:10.1007/978-3-319-29998-3_6

12-03-2016 | Staging | Article

Renal cell carcinoma: staging and surveillance

Staging of renal cell carcinoma (RCC) is essential to determine prognosis and to define appropriate treatment. This article describes the most appropriate staging evaluation of patients with RCC.

Dunnick NR. Abdom Radiol 2016; 41: 1079–1085. doi:10.1007/s00261-016-0692-0

17-03-2015 | Staging | Book chapter | Article

Classification of adult renal tumors and grading of renal cell carcinoma

Sukov WR & Cheville JC. In: Genitourinary Pathology. Edited by Magi-Galluzzi C, Przybycin CG. Springer New York, 2015. doi:10.1007/978-1-4939-2044-0_23

Epidemiology and prevention

05-10-2015 | Genitourinary cancers | Article

Gender differences in incidence and outcomes of urothelial and kidney cancer

This review summarizes the current understanding of the influence of gender on the incidence and outcomes of patients with bladder cancer, upper tract urothelial carcinoma and renal cell carcinoma.

Nat Rev Urol 2015; 12: 653. doi:10.1038/nrurol.2015.257

01-01-2015 | Renal cell carcinoma | Article

Epidemiology of renal cell carcinoma

This chapter provides an overview of the incidence, demographics and risk factors associated with the development of renal cell carcinoma.

Narayanan S et al. In: Kidney Cancer. Edited by Lara PN Jonasch E. Springer International Publishing, 2015. doi:10.1007/978-3-319-17903-2_1

04-07-2018 | Renal cell carcinoma | Article

Cancer in kidney transplant recipients

Au E, Wong G, Chapman JR. Nat Rev Nephrol 2018. doi:10.1038/s41581-018-0022-6

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