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Medicine Matters oncology

Remetinostat (SHAPE) is a topical histone deacetylase (HDAC) inhibitor, which has been tested in patients with stage IA–IIA MF in a phase II trial. The use of remetinostat gel led to a clinically significant reduction in the severity of skin lesions, and preliminary data also supports a meaningful reduction in the severity of pruritus [6].