Medicine Matters oncology

Features: In studies, patient have presented more commonly with diabetic ketoacidosis than with severe hyperglycemia [4]. HCPs should suspect diabetic ketoacidosis (DKA) if any of the following symptoms are present: feeling unwell or thirsty, polyuria, weight loss, drowsiness, or dizziness.

Investigations: Hemoglobin A1c (HbA1c), blood glucose (BM stix) pre- and post-meals, urinalysis, and a C-Peptide test to check for insulin production where blood glucose >20 mmol/L. A venous blood gas may be worthwhile to assess if the patient is acidotic.

Management: Most patients with type I diabetes should be treated with insulin, however seeking endocrinology advice is worthwhile given the morbidity associated with DKA and the need for dietetic changes and monitoring in the longer term.  In the event of a patient presenting with DKA, professionals should follow local or national acute management guidance.