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10-01-2017 | Multiple myeloma | Article

Multiple myeloma in 2016: Fresh perspectives on treatment and moments of clarity

Authors: Prashant Kapoor, S. Vincent Rajkumar

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Abstract

Data obtained in the past year underscored the benefit of a triplet regimen comprising bortezomib, lenalidomide, and dexamethasone for patients with newly-diagnosed multiple myeloma, and have provided high-level evidence supporting the safety of adding daratumumab to standard-of-care doublets for those with relapsed and/or refractory disease. As a result, achieving minimal residual disease-negativity at any stage of myeloma is now a realistic possibility.

Nat Rev Clin Oncol 2017; 14: 73–74. doi:10.1038/nrclinonc.2016.221