Schreuer M et al. Lancet Oncol 2017; 18(4): 464-472. doi:10.1016/S1470-2045(17)30171-7 Please follow the link below to view this article in full on a third party website. Note that a subscription or payment may be required. https://doi.org/10.1016/S1470-2045(17)30171-7