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Melanoma

Journal articles and book chapters

02-04-2019 | Immunotherapy | Video | Article

Researcher comment: The impact of lifestyle factors on the gut microbiome and immunotherapy response

Christine Spencer outlines her study investigating the effect of diet and supplements on gut microbiota and response to anti-PD-1 therapy in patients with metastatic melanoma, and discusses how the findings may be relevant to other tumor types (3:43).

12-12-2018 | Immunotherapy | Feature | Article

Hyperprogression as a response to immunotherapy: ‘A serious downside’

In light of recent reports of hyperprogression in response to treatment with cancer immunotherapy, medwireNews spoke to medical oncologist Razelle Kurzrock (University of California, San Diego, La Jolla, USA) about the phenomenon, the implications for therapy, and future directions for research.

20-08-2018 | Metastatic melanoma | Article

Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma

Auslander N et al. Nat Med 2018; 24: 1545–1549.

05-06-2018 | Radiotherapy | Article

Safety of combining radiotherapy with immune-checkpoint inhibition

Hwang WL et al. Nat Rev Clin Oncol 2018. doi: 10.1038/s41571-018-0046-7

10-04-2018 | Response criteria | Article

iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics

Seymour L et al. Lancet Oncol 2017; 18(3): e143–e152. doi:10.1016/S1470-2045(17)30074-8

07-03-2018 | Immunotherapy | Article

Gastrointestinal toxicity of immune checkpoint inhibitors: from mechanisms to management

Samaan MA et al. Nat Rev Gastroenterol Hepatol 2018; 15:222–234. doi:10.1038/nrgastro.2018.1

06-03-2018 | Immunotherapy | Article

Enhancing cancer immunotherapy using antiangiogenics: opportunities and challenges

Fukumura et al. Nat Rev Clin Oncol 2018. doi:10.1038/nrclinonc.2018.29

16-02-2018 | Immunotherapy | Article

Using immunotherapy to boost the abscopal effect

Ngwa W et al. Nat Rev Cancer 2018; 18: 313–322. doi:10.1038/nrc.2018.6

17-01-2018 | Melanoma | Article

Liquid biomarkers in melanoma: Detection and discovery

Lim SY et al. Mol Cancer 2018; 17:8. doi: 10.1186/s12943-018-0757-5

10-01-2018 | Melanoma | Article

Humanistic burden of disease for patients with advanced melanoma in Canada

Cheung WY et al. Support Care Cancer 2018. doi: 10.1007/s00520-017-4025-9

03-01-2018 | Melanoma | Article

Follow-up recommendations after diagnosis of primary cutaneous melanoma: a population-based study in new south wales, Australia

Read RL et al. Ann Surg Oncol. 2018; 25: 617. doi: 10.1245/s10434-017-6319-z

15-12-2017 | Melanoma | Article

Prognostic significance of RBP2-H1 variant of JARID1B in melanoma

Kuźbicki Ł et al. BMC Cancer 2017; 17: 854. doi: 10.1186/s12885-017-3836-x

07-11-2017 | Melanoma | Article

Clinicopathological predictors of recurrence in nodular and superficial spreading cutaneous melanoma: a multivariate analysis of 214 cases

Pizzichetta MA, Massi D, Mandalà M et al. J Transl Med 2017; 15:227. doi:10.1186/s12967-017-1332-3

30-10-2017 | Melanoma | Article

PET and SPECT imaging of melanoma: The state of the art

Wei W et al. Eur J Nucl Med Mol Imaging 2018; 45: 132. doi:10.1007/s00259-017-3839-5

09-10-2017 | Dabrafenib | Article

Long-Term Outcomes in Patients With BRAF V600-Mutant Metastatic Melanoma Who Received Dabrafenib Combined With Trametinib

Long G et al. J Clin Oncol 2018; 36(7): 667-673. doi:10.1200/JCO.2017.74

05-10-2017 | Melanoma | Article

Ipilimumab and early signs of pulmonary toxicity in patients with metastastic melanoma: a prospective observational study

Franzen D et al. Cancer Immunol Immunother 2017. doi: 10.1007/s00262-017-2071-2

02-10-2017 | Melanoma | Article

Melanoma subtypes demonstrate distinct PD-L1 expression profiles

Kaunitz et al. characterize programmed death-ligand 1 expression prevalence, patterns and levels among patients with various types of melanoma in an effort to determine whether there may be any relationship.

Laboratory Investigation 2017; 97, 1063–1071; doi:10.1038/labinvest.2017.64

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