Solid Pseudopapillary Neoplasm of the Pancreas Associated with Familial Adenomatous Polyposis

Tadahisa Inoue; Yuji Nishi; Fumihiro Okumura; Takashi Mizushima; Hirotada Nishie; Hiroyasu Iwasaki; Kaiki Anbe; Takanori Ozeki; Kenta Kachi; Shigeki Fukusada; Yuta Suzuki; Akira Mizuno; Masaki Kajikawa; Kazuko Watanabe; Hitoshi Sano

doi:10.2169/internalmedicine.54.4061

CASE REPORTS

Solid Pseudopapillary Neoplasm of the Pancreas Associated with Familial Adenomatous Polyposis

Tadahisa Inoue, Yuji Nishi, Fumihiro Okumura, Takashi Mizushima, Hirotada Nishie, Hiroyasu Iwasaki, Kaiki Anbe, Takanori Ozeki, Kenta Kachi, Shigeki Fukusada, Yuta Suzuki, Akira Mizuno, Masaki Kajikawa, Kazuko Watanabe, Hitoshi Sano

Author information

Tadahisa Inoue
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Yuji Nishi
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Fumihiro Okumura
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Takashi Mizushima
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Hirotada Nishie
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Hiroyasu Iwasaki
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Kaiki Anbe
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Takanori Ozeki
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Kenta Kachi
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Shigeki Fukusada
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Yuta Suzuki
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan
Akira Mizuno
Department of Surgery, Gifu Prefectural Tajimi Hospital, Japan
Masaki Kajikawa
Department of Surgery, Gifu Prefectural Tajimi Hospital, Japan
Kazuko Watanabe
Department of Pathology, Gifu Prefectural Tajimi Hospital, Japan
Hitoshi Sano
Department of Gastroenterology, Gifu Prefectural Tajimi Hospital, Japan

Keywords: solid pseudopapillary neoplasm, familial adenomatous polyposis, β-catenin, endoscopic ultrasound-guided fine-needle aspiration

JOURNAL OPEN ACCESS

2015 Volume 54 Issue 11 Pages 1349-1355

DOI https://doi.org/10.2169/internalmedicine.54.4061

Details

Abstract

A man in his thirties visited our hospital for an evaluation of a 12×10-mm pancreatic solid tumor that was accidentally detected on computed tomography performed for follow-up of familial adenomatous polyposis (FAP). We diagnosed the patient with a solid pseudopapillary neoplasm (SPN) based on endoscopic ultrasound-guided fine-needle aspiration, and he underwent pancreaticoduodenectomy. Small SPN tumors appear as solid tumors, without typical features of SPN, making the definitive diagnosis more difficult. The genetic background of FAP patients can predispose them to SPN, and imaging of the pancreas should be performed at prescribed intervals in FAP patients.

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