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Usefulness of staging laparoscopy for advanced gastric cancer

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Abstract

Purpose

The aim of this study was to clarify the usefulness of staging laparoscopy for planning the treatment strategy in patients with advanced gastric cancer.

Methods

This was a retrospective study of patients with gastric cancer who underwent staging laparoscopy. The patients were divided into three groups according to the presence/absence of peritoneal metastasis (P) and positive peritoneal cytology (CY): P negative (0) CY0, P0CY positive (1), and P1CY1. The treatment strategy after staging laparoscopy was as follows: (1) surgery for the P0CY0 group, (2) surgery with neoadjuvant chemotherapy (NAC) for the P0CY1 group, and (3) chemotherapy for the P1CY1 group. Survival was estimated by the Kaplan-Meier method and statistical differences were analyzed by the log-rank test.

Results

Thirty-four patients were included in this study: 11 in the P0CY0 group, 13 in the P0CY1 group, and 10 in the P1CY1 group. A gastrectomy was done in 11, 10, and no patients, respectively. The survival rate of the P0CY0 patients was significantly better than that of the P0CY1 or P1CY1 patients (P = 0.0106 and 0.0031, respectively).

Conclusion

Staging laparoscopy is useful for planning the treatment strategy and estimating the prognosis of patients with advanced gastric cancer.

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References

  1. Japanese Gastric Cancer Association. Japanese classification of gastric carcinoma. 2nd English edition. Gastric Cancer 1998;1:10–24.

    Article  PubMed  Google Scholar 

  2. Sasako M, Maruyama K, Kinoshita T, Shimada Y, Shirao K. Neoadjuvant chemotherapy for gastric cancer: Indication and trial setting (in Japanese). Shokakigeka 1992;15:159–167.

    Google Scholar 

  3. Ikeguchi M, Miyake T, Matsunaga T, Yamamoto M, Fukumoto Y, Yamada Y, et al. Recent results of therapy for scirrhous gastric cancer. Surg Today 2009;39:290–294.

    Article  CAS  PubMed  Google Scholar 

  4. Blackshaw GRJC, Barry JD, Edwards P, Allison MC, Thomas GV, Lewis WG. Laparoscopy significantly improves the perceived preoperative stage of gastric cancer. Gastric Cancer 2003;6:225–229.

    Article  PubMed  Google Scholar 

  5. D’Ugo DM, Persiani R, Caracciolo F, Ronconi P, Coco C, Picciocchi A. Selection of locally advanced gastric carcinoma by preoperative staging laparoscopy. Surg Endosc 1997;11:1159–1162.

    Article  PubMed  Google Scholar 

  6. Lowy AM, Mansfield PF, Leach SD, Ajani J. Laparoscopic staging for gastric cancer. Surgery 1996;119:611–614.

    Article  CAS  PubMed  Google Scholar 

  7. Lavonius MI, Gullichsen R, Salo S, Sonninen P, Ovaska J. Staging of gastric cancer: A study with spiral computed tomography, ultrasonography, laparoscopy, and laparoscopic ultrasonography. Surg Laparosc Endosc Percutan Tech 2002;12:77–81.

    Article  PubMed  Google Scholar 

  8. Gallardo-Rincon D, Onate-Ocana LF, Calderillo-Ruiz G. Neoadjuvant chemotherapy with P-ELF (cisplatin, etoposide, leucovorin, 5-fluorouracil) followed by radical resection in patients with initially unresectable gastric adenocarcinoma: a phase II study. Ann Surg Oncol 2000;7:45–50.

    Article  CAS  PubMed  Google Scholar 

  9. Koizumi W, Narahara H, Hara T, Takagane A, Akiya T, Takagi M, et al. S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer (SPIRITS trial): a phase III study. Lancet Oncol 2008;9:215–221.

    Article  CAS  PubMed  Google Scholar 

  10. Cutsem EV, Moiseyenko VM, Tjulandin S, Majlis A, Constenla M, Boni C, et al. Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 study group. J Clin Oncol 2006;24:4991–4997.

    Article  PubMed  Google Scholar 

  11. Bonenkamp JJ, Songun I, Hermans J, van de Velde CJH. Prognostic value of positive cytology findings from abdominal washings in patients with gastric cancer. Br J Surg 1996;83:672–674.

    Article  CAS  PubMed  Google Scholar 

  12. Kodera Y, Yamamura Y, Shimizu Y, Torii A, Hirai T, Yasui K, et al. Peritoneal washing cytology: prognostic value of positive findings in patients with gastric carcinoma undergoing a potentially curative resection. J Surg Oncol 1999;72:60–65.

    Article  CAS  PubMed  Google Scholar 

  13. Nakagawa S, Nashimoto A, Yabusaki H. Role of staging laparoscopy with peritoneal lavage cytology in the treatment of locally advanced gastric cancer. Gastric Cancer 2007;10:29–34.

    Article  CAS  PubMed  Google Scholar 

  14. Yano M, Tsujinaka T, Shiozaki H, Inoue M, Sekimoto M, Doki Y, et al. Appraisal of treatment strategy by staging laparoscopy for locally advanced gastric cancer. World J Surg 2000;24:1130–1136.

    Article  CAS  PubMed  Google Scholar 

  15. Sotiropoulos GC, Kaiser GM, Lang H, Treckmann J, Brokalaki EI, Pottgen C, et al. Staging laparoscopy in gastric cancer. Eur J Med Res 2005;10:88–91.

    CAS  PubMed  Google Scholar 

  16. Burke EC, Karpeh MS, Conlon KC, Brennan MF. Laparoscopy in the management of gastric adenocarcinoma. Ann Surg 1997;225:262–267.

    Article  CAS  PubMed  Google Scholar 

  17. Kriplani AK, Kapur BML. Laparoscopy for pre-operative staging and assessment of operability in gastric carcinoma. Gastrointest Endosc 1991;37:441–443.

    Article  CAS  PubMed  Google Scholar 

  18. Lehnert T, Rudek B, Kienle P, Buhl K, Herfarth C. Impact of diagnostic laparoscopy on the management of gastric cancer: prospective study of 120 consecutive patients with primary gastric adenocarcinoma. Br J Surg 2002;89:471–475.

    Article  CAS  PubMed  Google Scholar 

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Authors and Affiliations

  1. Department of Surgery, Japanese Red Cross Kyoto Daiichi Hospital, 15-749 Honmachi, Higashiyama-ku, Kyoto, 605-0981, Japan

    Hiroki Shimizu

  2. Department of Surgery, Sakai Municipal Hospital, Sakai, Osaka, Japan

    Hiroshi Imamura, Katsuya Ohta, Yasuhiro Miyazaki, Tomono Kishimoto, Mutsumi Fukunaga, Hiroki Ohzato, Masayuki Tatsuta & Hiroshi Furukawa

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  1. Hiroki Shimizu
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  2. Hiroshi Imamura
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  3. Katsuya Ohta
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  4. Yasuhiro Miyazaki
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  5. Tomono Kishimoto
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  6. Mutsumi Fukunaga
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  7. Hiroki Ohzato
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  8. Masayuki Tatsuta
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  9. Hiroshi Furukawa
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Shimizu, H., Imamura, H., Ohta, K. et al. Usefulness of staging laparoscopy for advanced gastric cancer. Surg Today 40, 119–124 (2010). https://doi.org/10.1007/s00595-009-4017-6

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  • DOI: https://doi.org/10.1007/s00595-009-4017-6

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