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Hemodynamics of intrahepatic cholangiocarcinoma: Evaluation with single-level dynamic CT during hepatic arteriography

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Abstract

Background: We determined the radiologic characteristics of intrahepatic cholangicarcinoma (ICC) on single-level dynamic computed tomography during hepatic arteriography (CTHA) and assessed the hemodynamics of the tumor.

Methods: Eleven patients with pathologically confirmed ICC underwent single-level dynamic CTHA. After placing the catheter tip in the proper hepatic artery and running a 30-s continuous scan, scanning was performed every 15 or 30 s for 120 s. The change of contrast-enhancement pattern of the ICCs were interpreted retrospectively.

Results: The pattern of enhancement was classified into two types: vascular and hypovascular. In the vascular type, the contrast enhancement gradually spread from each intratum oral artery and became mottled. It changed from a mottled and hypoattenuated pattern to an even and hyperattenuated appearance in comparison with the adjacent liver approximately 120 s after the injection of contrast agent. In the hypovascular type, the tumor was barely enhanced and remained hypoattenuated compared with the adjacent liver at 120 s after the beginning of the injection. The 11 ICCs were classified into eight vascular types and three hypovascular types. Intratumoral arteries were visualized in nine tumors: eight vascular types and one hypovascular type.

Conclusion: The contrast-enhancement pattern of ICC on single-level dynamic CTHA is related to the intratumoral artery.

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Authors and Affiliations

  1. Department of Academic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan

    F. Miura, S. Okazumi, W. Takayama, T. Asano, H. Makino, K. Shuto & T. Ochiai

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  1. F. Miura
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  2. S. Okazumi
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  3. W. Takayama
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  4. T. Asano
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  5. H. Makino
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  6. K. Shuto
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  7. T. Ochiai
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Correspondence to F. Miura.

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Present address: Department of Surgery, Teikyo University, School of Medicine, 2-11-1, Kaga, Itabashi-ku, Tokyo, 173-8605, Japan

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Miura, F., Okazumi, S., Takayama, W. et al. Hemodynamics of intrahepatic cholangiocarcinoma: Evaluation with single-level dynamic CT during hepatic arteriography. Abdom Imaging 29, 467–471 (2004). https://doi.org/10.1007/s00261-004-0177-4

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  • DOI: https://doi.org/10.1007/s00261-004-0177-4

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