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Localization of small islet-cell tumors. Preoperative and intraoperative ultrasound, computed tomography, arteriography, digital subtraction angiography, and pancreatic venous sampling

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Abstract

A total of 42 islet-cell tumors were examined between 1972 and 1984. Problems of localization were only encountered in 31 tumors less than 2 cm in diameter. Of 31 small tumors, 27 were correctly localized using a combined diagnostic approach: ultrasound was successful in 12/20 tumors, CT in 9/21, angiography in 20/31, intraarterial digital subtraction angiography in 1/2, and pancreatic venous sampling in 13/16. The smallest tumor found by ultrasound and CT was 7 mm in diameter. Intraoperative ultrasound demonstrated all 9 insulinomas examined. Currently, the most useful techniques for localizing small islet-cell tumors are ultrasound, CT, and angiography. CT is particularly useful for tumor staging. Improvement of non-invasive diagnostic techniques will obviate the need for transhepatic blood sampling.

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Authors and Affiliations

  1. Department of Surgery, Institute for Clinical Radiology, Mainz, Germany

    Rolf W. Günther, Klaus J. Klose, K. Rückert, J. Beyer, F. P. Kuhn & H. J. Klotter

  2. Department of Endocrinology, University of Mainz, Mainz, Germany

    Rolf W. Günther, Klaus J. Klose, K. Rückert, J. Beyer, F. P. Kuhn & H. J. Klotter

Authors
  1. Rolf W. Günther
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  2. Klaus J. Klose
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  3. K. Rückert
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  4. J. Beyer
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  5. F. P. Kuhn
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  6. H. J. Klotter
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Günther, R.W., Klose, K.J., Rückert, K. et al. Localization of small islet-cell tumors. Preoperative and intraoperative ultrasound, computed tomography, arteriography, digital subtraction angiography, and pancreatic venous sampling. Gastrointest Radiol 10, 145–152 (1985). https://doi.org/10.1007/BF01893089

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  • DOI: https://doi.org/10.1007/BF01893089

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