Top

03-03-2018 | Hematologic cancers | Article

Sexual health in patients with hematological malignancies: a neglected issue

Journal: Supportive Care in Cancer

Authors: Pasquale Niscola, Fabio Efficace, Elisabetta Abruzzese

Publisher: Springer Berlin Heidelberg

Abstract

Current evidence, although limited, outlines that sexual dysfunction may represent a prominent part of the symptom burden experienced by the patients with hematologic malignancies (HM). However, despite their presumed negative effects on quality of life (QoL), sexual health is not typically considered in the QoL assessment of HM patients. In addition, very few studies have been conducted in this area. Therefore, it would be important to further investigate how newer drugs developed in recent years for patients with HM, including targeted therapies and impact on sexual health, and how this influence overall patients’ QoL outcomes.

Efficace F, Gaidano G, Lo-Coco F (2017 Aug 17) Patient-reported outcomes in hematology: is it time to focus more on them in clinical trials and hematology practice? Blood 130(7):859–866CrossRef

Abruzzese E (2017 Jul) The destiny of chronic myeloid leukeamia. Lancet Haematol 4(7):e303–e304CrossRef

Bevans M, El-Jawahri A, Tierney DK, Wiener L, Wood WA, Hoodin F, Kent EE, Jacobsen PB, Lee SJ, Hsieh MM, Denzen EM, Syrjala KL (2017 Apr) National Institutes of Health hematopoietic cell transplantation late effects initiative: the patient-centered outcomes working group report. Biol Blood Marrow Transplant 23(4):538–551CrossRef

Li Z, Mewawalla P, Stratton P, Yong AS, Shaw BE, Hashmi S, Jagasia M, Mohty M, Majhail NS, Savani BN, Rovó A (2015 Dec 1) Sexual health in hematopoietic stem cell transplant recipients. Cancer 121(23):4124–4131CrossRef

Olsson C, Berglund AL, Larsson M, Athlin E (2012 Sep) Patient’s sexuality—a neglected area of cancer nursing? Eur J Oncol Nurs 16(4):426–431CrossRef

Abruzzese E, Trawinska MM, de Fabritiis P, Baccarani M (2016 Aug) Management of pregnant chronic myeloid leukemia patients. Expert Rev Hematol 9(8):781–791CrossRef

Rovó A, Tichelli A, Passweg JR, Heim D, Meyer-Monard S, Holzgreve W, Gratwohl A, De Geyter C (2006 Aug 1) Spermatogenesis in long-term survivors after allogeneic hematopoietic stem cell transplantation is associated with age, time interval since transplantation, and apparently absence of chronic GvHD. Blood 108(3):1100–1105CrossRef

Haavisto A, Henriksson M, Heikkinen R, Puukko-Viertomies LR, Jahnukainen K (2016 Jul 15) Sexual function in male long-term survivors of childhood acute lymphoblastic leukemia. Cancer 122(14):2268–2276CrossRef

Kim IR, Kim SH, Ok ON, Kim SH, Lee S, Choi E, Kim SJ, Yoon DH, Lee MH (2017 May) Sexual problems in male vs. female non-Hodgkin lymphoma survivors: prevalence, correlates, and associations with health-related quality of life. Ann Hematol 96(5):739–747CrossRef

10.

Liptrott SJ, Shash E, Martinelli G (2011 Dec) Sexuality in patients undergoing haematopoietic stem cell transplantation. Int J Hematol 94(6):519–524CrossRef

11.

Thygesen KH, Schjødt I, Jarden M (2012 May) The impact of hematopoietic stem cell transplantation on sexuality: a systematic review of the literature. Bone Marrow Transplant 47(5):716–724CrossRef

12.

Nørskov KH, Schmidt M, Jarden M (2015 Aug) Patients’ experience of sexuality 1-year after allogeneic haematopoietic stem cell transplantation. Eur J Oncol Nurs 19(4):419–426CrossRef

13.

Olsson C, Sandin-Bojö AK, Bjuresäter K, Larsson M (2016) Changes in sexuality, body image and health related quality of life in patients treated for hematologic malignancies: a longitudinal study. Sex Disabil 34(4):367–388CrossRef

14.

Geyer HL, Andreasson B, Kosiorek HE, Dueck AC, Scherber RM, Martin KA, Butler KA, Harrison CN, Radia DH, Cervantes F, Kiladjian JJ, Reiter A, Birgegard G, Passamonti F, Senyak Z, Vannucchi AM, Paoli C, Xiao Z, Samuelsson J, Mesa RA (2016 Jun 15) The role of sexuality symptoms in myeloproliferative neoplasm symptom burden and quality of life: an analysis by the MPN QOL International Study Group. Cancer 122(12):1888–1896CrossRef

15.

WHO (2006) Defining sexual health: report of a technical consultation on sexual health, 28–31 January 2002. Geneva: World Health Organization

16.

Waterhouse J, Metcalfe MC (1986) Development of the sexual adjustment questionnaire. Oncol Nurs Forum 13(3):53–59PubMed

17.

Hopwood P, Fletcher I, Lee A, Al Ghazal S (2001 Jan) A body image scale for use with cancer patients. Eur J Cancer 37(2):189–197CrossRef

18.

Aaronson NK, Ahmedzai S, Bergman B, Bullinger M, Cull A, Duez NJ, Filiberti A, Flechtner H, Fleishman SB, de Haes JC et al (1993 Mar 3) The European Organization for Research and Treatment of Cancer QLQ-C30: a quality-of-life instrument for use in international clinical trials in oncology. J Natl Cancer Inst 85(5):365–376CrossRef

19.

Scherber R, Dueck AC, Johansson P, Barbui T, Barosi G, Vannucchi AM, Passamonti F, Andreasson B, Ferarri ML, Rambaldi A, Samuelsson J, Birgegard G, Tefferi A, Harrison CN, Radia D, Mesa RA (2011 Jul 14) The myeloproliferative neoplasm symptom assessment form (MPN-SAF): international prospective validation and reliability trial in 402 patients. Blood 118(2):401–408CrossRef

20.

Gerds AT (2016 Jun 15) Let’s talk about sex[uality]-related symptom burden in myeloproliferative neoplasms. Cancer 122(12):1804–1806CrossRef

Medicine Matters Oncology

Abstract