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Hematologic cancers

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Scientific summary

Diffuse large B-cell lymphoma management: Exploring novel treatment strategies

Diffuse large B-cell lymphoma management: Exploring novel treatment strategies

This program was made possible thanks to independent educational sponsorship from MorphoSys.

medwireNews editor's pick

‘Reassuring’ childbirth rate reported for Hodgkin lymphoma survivors

Newborn baby

The birth rate for women who are relapse-free after treatment for Hodgkin lymphoma has risen in recent years, becoming comparable with that of the general population regardless of disease stage or treatment.

medwireNews editor's pick

Liposomal cytarabine–daunorubicin prolongs high-risk secondary AML survival

IV drip 2

Phase III trial findings support the use of a liposome-encapsulated formulation of cytarabine and daunorubicin in older patients with a new diagnosis of high-risk secondary acute myeloid leukemia.

medwireNews@ASCO2018

Hematologic cancers coverage at ASCO Annual Meeting 2018

ASCO 2018
Expert opinion

Discontinuing tyrosine kinase inhibitors in chronic myeloid leukemia

Ehab Atallah

Tyrosine kinase inhibitor (TKI) treatment of chronic myeloid leukemia (CML) can result in prolonged and deep responses in many patients. In such cases, can TKIs be safely discontinued to avoid adverse side effects and costs? Etab Atallah (Medical College of Wisconsin, USA) discusses the current issues surrounding TKI discontinuation in CML.

13-08-2018 | Waldenström macroglobulinemia | News

Ibrutinib monotherapy promising for untreated Waldenström macroglobulinemia

Phase II trial results suggest that the Bruton tyrosine kinase inhibitor ibrutinib has high activity and is well tolerated in symptomatic, treatment-naïve patients with Waldenström macroglobulinemia.

13-08-2018 | FDA | News

Mogamulizumab-kpkc approved for rare NHL subtypes

Read more on this US FDA decision here

03-08-2018 | Hodgkin lymphoma | News

‘Reassuring’ childbirth rate reported for Hodgkin lymphoma survivors

The birth rate for women who are relapse-free after treatment for Hodgkin lymphoma has risen in recent years, becoming comparable with that of the general population regardless of disease stage or treatment.

Case reports and studies

09-03-2017 | Lymphoma | Case report | Article

Cutaneous T-cell lymphoma

In this case report, an 83-year-old female presented to the physician with a progressing pruritic cutaneous rash that started 8 years ago. Read this review to understand how her condition was managed.

In: Management of Lymphomas: A Case-Based Approach. Edited by Zain J & Kwak LW. Springer International Publishing, 2017. doi:10.1007/978-3-319-26827-9_10

09-03-2017 | Lymphoma | Case report | Article

CNS lymphoma

This  case report describes the presentation, workup and staging, and treatment recommendations for a 56-year-old woman who presented with vertigo, headaches, and frequent falls.

In: Management of Lymphomas: A Case-Based Approach. Edited by Zain J & Kwak LW. Springer International Publishing, 2017. doi:10.1007/978-3-319-26827-9_14

14-03-2017 | Lymphoma | Case report | Article

SLL and CLL

A 72-year-old man with a history of diabetes mellitus, hypertension, and hypercholesterolemia self-palpated a left submandibular lump – read how the City of Hope team approached his case.

In: Management of Lymphomas: A Case-Based Approach. Edited by Zain J & Kwak LW. Springer International Publishing, 2017. doi:10.1007/978-3-319-26827-9_4

Journal articles and book chapters

05-06-2018 | Radiotherapy | Article

Safety of combining radiotherapy with immune-checkpoint inhibition

Hwang WL et al. Nat Rev Clin Oncol 2018. doi: 10.1038/s41571-018-0046-7

31-05-2018 | B-cell lymphoma | Article

Phase 3 Trial of Ibrutinib plus Rituximab in Waldenström’s Macroglobulinemia

Dimopoulos MA et al. N Engl J Med 2018; 378(25): 2399-2410. doi:10.1056/NEJMoa1802917

20-03-2018 | Multiple myeloma | Article

Patient-reported outcomes in relapsed/refractory multiple myeloma: a systematic review

Sparano F et al. Support Care Cancer 2018; 26: 2075. doi:10.1007/s00520-018-4137-x

03-03-2018 | Hematologic cancers | Article

Sexual health in patients with hematological malignancies: a neglected issue

Niscola P et al. Support Care Cancer 2018; 26(6): 1699-1701. doi:10.1007/s00520-018-4124-2.

27-02-2018 | Acute leukemia | Article

Therapy for children and adults with mixed phenotype acute leukemia: a systematic review and meta-analysis

Maruffi M et al. Leukemia 2018. doi:10.1038/s41375-018-0058-4

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