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21-07-2016 | Endocrine cancers | Book chapter | Article

6. Genetic Evaluation of the Patient with Medullary Thyroid Cancer

Author: Jennifer L. Geurts

Publisher: Springer International Publishing

Abstract

The hereditary form of medullary thyroid cancer (MTC) is termed multiple endocrine neoplasia type 2 (MEN2). The RET gene is the only gene known to cause MEN2 syndrome, and up to 98 % of patients with MEN2 have an identifiable pathogenic mutation in this gene.

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