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19-10-2021 | EMA | News

approvalsWatch

EMA gives green light for first-line use of lenvatinib plus pembrolizumab in advanced RCC

Author:
Hannah Kitt

medwireNews: The combination of lenvatinib and pembrolizumab has received a positive opinion from the EMA’s Committee for Medicinal Products for Human Use for the first-line treatment of advanced renal cell carcinoma (RCC).

This decision follows the positive results of the phase 3 CLEAR trial, which showed a significant progression-free and overall survival benefit with use of lenvatinib plus pembrolizumab relative to sunitinib.

The combination of the multikinase inhibitor plus the PD-1 inhibitor was approved for the same indication by the US FDA earlier this year.

medwireNews is an independent medical news service provided by Springer Healthcare Ltd. © 2021 Springer Healthcare Ltd, part of the Springer Nature Group

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