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Hematologic cancers: Risk factors and epidemiology

Journal articles and book chapters

10-01-2018 | Acute myeloid leukemia | Article

Mutations in DNMT3A, U2AF1, and EZH2 identify intermediate-risk acute myeloid leukemia patients with poor outcome after CR1

Saygin C et al. Blood Cancer J 2018; doi:10.1038/s41408-017-0040-9

18-12-2017 | Acute myeloid leukemia | Article

Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia

Rothenberg-Thurley M et al. Leukemia 2017; doi:10.1038/leu.2017.350

31-10-2017 | Acute myeloid leukemia | Article

Epidemiological, genetic, and clinical characterization by age of newly diagnosed acute myeloid leukemia based on an academic population-based registry study (AMLSG BiO)

Nagel G, Weber D, Fromm E et al. Ann Hematol 2017; 96:1993. doi:10.1007/s00277-017-3150-3

12-09-2017 | Pediatric leukemia | Article

Residential magnetic fields exposure and childhood leukemia: a population-based case–control study in California

Kheifets L et al. Cancer Causes Control 2017; 28: 1117–1123. doi:10.1007/s10552-017-0951-6

25-08-2017 | Lymphoma | Article

Vitamin D insufficiency is associated with an increased risk of early clinical failure in follicular lymphoma

​​​​​​​Blood Cancer J 2017; 7: e595. doi:10.1038/bcj.2017.70

28-07-2017 | Hodgkin lymphoma | Article

Therapeutic radiation for lymphoma and risk of second primary malignant mesothelioma

Chang ET et al. Cancer Causes Control 2017 28: 971. doi:10.1007/s10552-017-0929-4


08-06-2017 | Acute myeloid leukemia | Article

Predictors of thrombohemorrhagic early death in children and adolescents with t(15;17)-positive acute promyelocytic leukemia treated with ATRA and chemotherapy

Abla O et al. Ann Hematol 2017; 96: 1449–1456. doi:10.1007/s00277-017-3042-6


16-09-2016 | Hematologic cancers | Book chapter | Article

Risk factors, etiology, and pathogenesis

In this chapter, the authors review current knowledge of the risk factors for and molecular 
pathogenesis of the most common lymphomas.

In: Handbook of Lymphoma. Edited by Younes A. Springer International Publishing, 2016. doi:10.1007/978-3-319-08467-1_2

02-09-2016 | Hematologic cancers | Book chapter | Article

Epidemiology of hematologic malignancies

Batista JL, Birmann BM, & Epstein MM. In: Pathology and Epidemiology of Cancer. Edited by Loda M et al. Springer International Publishing, 2017. doi:10.1007/978-3-319-35153-7_29

18-08-2016 | Chronic myeloid leukemia | Book chapter | Article

Epidemiology of chronic myeloid leukemia

Höglund M, Sandin F, & Simonsson B. In: Chronic Myeloid Leukemia. Edited by Hehlmann R. Springer International Publishing, 2016. doi:10.1007/978-3-319-33198-0_7

24-05-2016 | Pediatric leukemia | Article

Childhood leukaemia and distance from power lines in California: A population-based case-control study

Crespi et al. evaluate claims of an increased risk of childhood leukemia associated with living near high-voltage electric power transmission lines that extend to distances at which magnetic fields from lines are negligible.

Crespi CM et al. Br J Cancer 2016; 115: 122–128. doi:10.1038/bjc.2016.142

19-03-2016 | Pediatric leukemia | Book chapter | Article

Etiology and prevention of acute leukemias in children

This chapter from Núñez-Enríquez et al. summarizes the scientific evidence on the etiology and prevention of acute leukemias in children.

Núñez-Enríquez JC et al. In: Etiology of Acute Leukemias in Children. Edited by Mejía-Aranguré J. Springer International Publishing Switzerland, 2016. doi:10.1007/978-3-319-05798-9

17-03-2016 | Hematologic cancers | Article

The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study

In this original research article, Iqbal and colleagues observe an increased risk of leukemia in women with a BRCA2 mutation who have received chemotherapy for breast cancer.

Br J Cancer 2016; 114: 1160–1164. doi:10.1038/bjc.2016.58

07-03-2016 | Pediatric leukemia | Article

Obesity and metabolic syndrome among adult survivors of childhood leukemia

 This review summarizes the recent literature on the prevalence and risk factors for obesity and metabolic syndrome in childhood acute lymphoblastic leukemia survivors. The authors also suggest lifestyle changes with the potential to mitigate risk.

Gibson TM et al. Curr Treat Options in Oncol 2016; 17: 17. doi:10.1007/s11864-016-0393-5

07-02-2016 | Hematologic cancers | Book chapter | Article

Epidemiology and etiology of non-hodgkin lymphoma

Chiu BCH & Hou N. In: Non-Hodgkin Lymphoma. Edited by Evens AM & Blum KA. Springer international Publishing, 2015. doi:10.1007/978-3-319-13150-4_1

12-01-2016 | Pediatric leukemia | Article

Supplemental folic acid in pregnancy and childhood cancer risk

In this US study, Mortensen et al. investigated the association between maternal intake of folic acid supplementation in pregnancy and offspring risk of childhood cancer in a nationwide cohort study in a Norwegian population.

Mortensen JH et al. Br J Cancer 2016; 114: 71–75. doi:10.1038/bjc.2015.446

23-11-2015 | Multiple myeloma | Article

Family history of hematologic malignancies and risk of multiple myeloma: differences by race and clinical features

In this population-based, case-control study, the authors found that an increased risk of multiple myeloma in the Black population and variations in clinical features may be attributed to a shared germline and environmental susceptibility.

VanValkenburg ME et al. Cancer Causes Control 2016; 27: 81–91. doi:10.1007/s10552-015-0685-2

04-11-2015 | Pediatric leukemia | Article

Risk for childhood leukemia associated with maternal and paternal age

This meta-analysis from Sergentanis et al. examines the associations between parental age with acute lymphoblastic leukemia and acute myeloid leukemia.

Sergentanis TN et al. Eur J Epidemiol 2015; 30: 1229–1261. doi:10.1007/s10654-015-0089-3

16-09-2015 | Hematologic cancers | Article

Acute lymphoblastic leukemia: an assessment of international incidence, survival, and disease burden

This original research paper describes the international incidence of acute lymphoblastic leukemia and suggests that while relative survival rates are near 90% in children survival remains poor in adults.

Katz AJ et al. Cancer Causes Control 2015; 26: 1627–1642. doi:10.1007/s10552-015-0657-6

01-09-2015 | Hematologic cancers | Article

Risk factors and time to symptomatic presentation in leukaemia, lymphoma and myeloma

Howell et al determine that hematological malignancies have varying presentations by subtype but there is a worrying lack of public awareness of the differing clinical presentations, which is causing delayed diagnosis.

Br J Cancer 2015; 113: 1114–1120. doi:10.1038/bjc.2015.311

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