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CheckMate 817

CheckMate 817 is phase IV study evaluating the safety profile of combined nivolumab–ipilimumab treatment in individuals who have not received prior systemic treatment for stage IV or recurrent non-small-cell lung cancer. It is a multicohort study that includes certain special populations, such as patients with poor functional status and those with high tumor mutational burden.


Fabrice Barlesi discusses the CheckMate 817 trial and whether first-line nivolumab–ipilimumab is a feasible option for certain subgroups of advanced non-small-cell lung cancer patients, such as those with poor functional status (3:32):

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At a glance: CheckMate lung cancer trials