Abstract
The principal management of primary soft tissue sarcoma is surgical resection. The clinical goal is resection with negative margins, preferably that extend 2 cm from the grossly determined border. This can be difficult to assess and is often limited by the presence of major neurovascular and bony structures. The majority of soft tissue sarcomas do not invade into bone unless there has been previous injury to bone or the lesion has an epithelioid component, such as synovial sarcoma.
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Brennan, M.F., Antonescu, C.R., Alektiar, K.M., Maki, R.G. (2016). General Statement as to Efficacy of Surgery, Chemotherapy, Radiation Therapy, and Immunotherapy. In: Management of Soft Tissue Sarcoma. Springer, Cham. https://doi.org/10.1007/978-3-319-41906-0_3
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