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Tissue Sampling

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Pulmonary Pathology

Abstract

The continuous development of new clinical, radio-logic, surgical, and pathologic techniques highlights an ever-changing practice of pathology. With reference to many locations in the body, and certainly in the lung, the pathologist is being asked to be more diagnostic with smaller and smaller samples. Immunohistochemistry, DNA probes, polymerase chain reactions, and other newer techniques entering diagnostic practice may lead to a diagnosis based on only a few cells. As in electron microscopy, the challenge will be to judge whether such samples are truly representative and whether the changes observed account for the patient’s disease. Pattern recognition on tissue sections is still valuable (see Chapter 4), but is being supplemented and in part replaced with some of these newer techniques.

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References

  1. Klassen KP, Anlyan AJ, Curtis GM. Biopsy of diffuse pulmonary lesions. Arch Surg 1949; 59: 694–704.

    Article  PubMed  CAS  Google Scholar 

  2. Chamberlain JM. Discussion of presentation on “mediastinoscopy.” J Thorac Cardiovasc Surg 1965; 49: 20.

    Google Scholar 

  3. McNeill TM, Chamberlain JM. Diagnostic anterior mediastinotomy. Ann Thorac Surg 1966; 2: 532–539.

    Article  PubMed  CAS  Google Scholar 

  4. Andersen HA, Fontana RS, Harrison EG, Jr. Transbronchoscopic lung biopsy in diffuse pulmonary disease. Dis Chest 1965; 48: 187–192.

    Article  PubMed  CAS  Google Scholar 

  5. Andersen HA, Fontana RS. Transbronchoscopic lung biopsy for diffuse pulmonary diseases: Techniques and results in 450 cases. Chest 1972; 62: 125–128.

    Article  PubMed  CAS  Google Scholar 

  6. Anderson H. Transbronchial lung biopsy for diffuse pulmonary diseases. Results in 939 patients. Chest 1978; 73: 734–736.

    Google Scholar 

  7. Prakash VBS, Stubbs SE. The bronchoscopy survey: Some reflections. Chest 1991; 100: 1660–1667.

    Article  PubMed  CAS  Google Scholar 

  8. Prakash VBS, Offord KP, Stubbs SE. Bronchoscopy in North America: The ACCP Survey. Chest 1991; 100: 1668–1675.

    Article  PubMed  CAS  Google Scholar 

  9. Ikeda S. Flexible bronchofiber scope. Ann Otol Rhinol Laryngol 1970; 79: 916–923.

    PubMed  CAS  Google Scholar 

  10. Kovnat DM, Rath GS, Anderson WM, Snider GL. Maximal extent of visualization of bronchial tree by flexible fiberoptic bronchoscopy. Am Rev Respir Dis 1974; 110: 88–90.

    PubMed  CAS  Google Scholar 

  11. Herf SM, Suratt PM, Arora NS. Deaths and complications associated with transbronchial lung biopsy. Am Rev Respir Dis 1977; 115: 708–711.

    PubMed  CAS  Google Scholar 

  12. Zavala DC. Pulmonary hemorrhage in fiberoptic trans-bronchial biopsy. Chest 1976; 70: 584–588.

    Article  PubMed  CAS  Google Scholar 

  13. Silverman I. A new biopsy needle. Am J Surg 1938; 40: 671–672.

    Article  Google Scholar 

  14. Gaensler EA. Open and closed lung biopsy. In: Sackner MA, ed. Diagnostic techniques in pulmonary disease. Part II. New York: Marcel-Dekker, 1980: 579– 615.

    Google Scholar 

  15. Wang KP, Terry P, Marsh B. Bronchoscopic needle aspiration of paratracheal tumors. Am Rev Respir Dis 1978; 118: 17–21.

    PubMed  CAS  Google Scholar 

  16. Wang KP, Marsh BR, Summer WR, Perry PB, Erozan YS, Baker RR. Transbronchial aspiration for diagnosis of lung cancer. Chest 1981; 80: 48–50.

    Article  PubMed  CAS  Google Scholar 

  17. Wang KP, Kaponik EF, Briff EJ, Khouri N, Erozan Y. Transbronchial needle aspiration of peripheral pulmonary nodular. Chest 1984; 86: 819–823.

    Article  PubMed  CAS  Google Scholar 

  18. Shure D, Fedullo PF. Transbronchial needle aspiration in the diagnosis of submucosal and peribronchial bronchogenic carcinoma. Chest 1985; 88: 49–51.

    Article  PubMed  CAS  Google Scholar 

  19. Bartlett JG, Alexander J, Mayhew J, Sullivan-Sigler N, Gorbach SL. Should fiberoptic bronchoscopy aspirates be cultured? Am Rev Respir Dis 1976; 114: 73–78.

    PubMed  CAS  Google Scholar 

  20. Winterbauer RH, Hutchinson JF, Reinhardt GN, et al. The use of quantitative cultures and antibody coating of bacteria to diagnose bacterial pneumonia by fiberoptic bronchoscopy. Am Rev Respir Dis 1983; 128: 98–103.

    PubMed  CAS  Google Scholar 

  21. Carrington CB, Gaensler EA. Clinical-pathologic approach to diffuse infiltrative lung disease. In: Thurlbeck W, Abell M, eds. The lung: structure and function. Baltimore: Williams & Wilkins, 1978: 58 –87.

    Google Scholar 

  22. Gaensler EA, Carrington CB. Open lung biopsy for chronic diffuse infiltrative lung disease: clinical, roentgenographic and physiological correlations in 502 patients. Ann Thorac Surg 1980; 30: 411 –426.

    Article  PubMed  CAS  Google Scholar 

  23. Churg A. An inflation procedure for open lung biopsies. Am J Surg Pathol 1983; 7: 69–71.

    Article  PubMed  CAS  Google Scholar 

  24. Churg A. Lung biopsy: Handling and diagnostic limitations. In: Thurlbeck WM, ed. Pathology of the lung. Stuttgart: Thieme, 1988: 67–78.

    Google Scholar 

  25. Miller RR, Nelems B. Gross examination of lung resection specimens. In: Thurlbeck WM, ed. Pathology of the lung. Stuttgart: Thieme, 1988: 79–93.

    Google Scholar 

  26. Thurlbeck WM. Examination of the lung: Autopsy. In: Thurlbeck WM, ed. Pathology of the lung. Stuttgart: Thieme, 1988: 95–100.

    Google Scholar 

  27. Katzenstein A-L A, Askin FB. Surgical pathology of non-neoplastic lung disease. 2d Ed. Philadelphia: WB Saunders, 1990: 1–8.

    Google Scholar 

  28. Gaensler EA, Ball-Moister M, Hamm J. Open lung biopsy in diffuse pulmonary disease. N Engl J Med 1964; 270: 1319–1331.

    Article  PubMed  CAS  Google Scholar 

  29. Gaensler EA, Carrington CB. Open biopsy for diffuse infiltrative lung disease. Ann Thorac Surg 1980; 40: 411–426.

    Article  Google Scholar 

  30. Greenman RL, Goodall PT, King D. Lung biopsy in immunocompromised hosts. Am J Med 1975; 59: 488496.

    Google Scholar 

  31. McLoud TC, Naidich DP. Thoracic diseases in the immunocompromised patient. Radiol Clin North Am 1992; 30: 525–554.

    PubMed  CAS  Google Scholar 

  32. Kovacs JA, Hiemenz JW, Macher AM, et al. Pneumonocystis carinii pneumonia: A comparison between patients with the acquired immunodeficiency syndrome and patients with other immunodeficiencies. Ann Intern Med 1984; 100: 663–671.

    Article  PubMed  CAS  Google Scholar 

  33. Limper AH, Offord KP, Smith TF, Martin WJ, II. Pneumonocystis carinii pneumonia: Differences in lung parasite number and inflammation in patients with and without AIDS. Am Rev Respir Dis 1989; 140: 1204–1209.

    Article  PubMed  CAS  Google Scholar 

  34. Sepkowitz KA, Brown AE, Telzak ED, Gottlieb S, Armstrong D. Pneumonocystis carinii pneumonia among patients without AIDS at a cancer hospital. JAMA 1992; 267: 832–837.

    Article  PubMed  CAS  Google Scholar 

  35. Luna MA, Cleary KR. Spectrum of pathologic manifestations of Pneumonocystis carinii pneumonia in patients with neoplastic diseases. Semin Diagn Pathol 1989; 6: 262–272.

    PubMed  CAS  Google Scholar 

  36. Raviglione MC. Extrapulmonary pneumocystosis: The first 50 cases. Rev Infect Dis 1990; 12: 1127–1138.

    Article  PubMed  CAS  Google Scholar 

  37. Pennington JE, Feldman NT. Pulmonary infiltrates and fever in patients with hematologic malignancy. Am J Med 1977; 62: 581–587.

    Article  PubMed  CAS  Google Scholar 

  38. Bodey GP, Powell RD, Hersh EM, Yeterian A, Freireich EJ. Pulmonary complications of acute leukemia. Cancer (Philadelphia) 1966; 19: 781–793.

    Article  CAS  Google Scholar 

  39. Bode FR, Pare JAP, Fraser RG. Pulmonary diseases in the compromised host. Medicine (Baltimore) 1974; 53: 255–293.

    CAS  Google Scholar 

  40. Feldman NT, Pennington JE, Ehrie MG. Transbronchial lung biopsy in the compromised host. JAMA 1977; 238: 1377–1379.

    Article  PubMed  CAS  Google Scholar 

  41. Sickles EA, Young VM, Greene WH, Wiernik PH. Pneumonia in acute leukemia. Ann Intern Med 1973; 79: 528534.

    Google Scholar 

  42. Sickles EA, Greene WH, Wicknik PM. Clinical presentation of infection in granulocytopenic patients. Arch Intern Med 1975; 135: 715–719.

    Article  PubMed  CAS  Google Scholar 

  43. Masur H, Shelhamer J, Parillo JE. The management of pneumonias in immunocompromised patients. JAMA 1985; 253: 1769–1773.

    Article  PubMed  CAS  Google Scholar 

  44. Jaffee JP, Maki DG. Lung biopsy in immunocompromised patients: one institution’s experience and an approach to management of pulmonary disease in the compromised host. Cancer (Philadelphia) 1981; 48: 1144–1153.

    Article  Google Scholar 

  45. Hiatt JR, Gong H, Mulder DG, Ramming KP. The value of open lung biopsy in the immunosuppressed patient. Surgery 1982; 92: 285–291.

    PubMed  CAS  Google Scholar 

  46. McCabe RE, Brooks RG, Mark JBD, Remington JS. Open lung biopsy in patients with acute leukemia. Am J Med 1985; 78: 609–616.

    Article  PubMed  CAS  Google Scholar 

  47. Rosenow EC, III, Wilson WR, Cockerill FR III. Pulmonary disease in the immunocompromised host. Mayo Clin Proc 1985; 60: 473–487.

    Article  PubMed  Google Scholar 

  48. Wilson WR, Cockerill FR, III, Rosenow EC III. Pulmonary disease in the immunocompromised host. Mayo Clin Proc 1985; 60: 610–631.

    Article  PubMed  CAS  Google Scholar 

  49. Rosenow EC, III. The spectrum of drug-induced pulmonary disease. Ann Intern Med 1972; 77: 977–991.

    Article  PubMed  CAS  Google Scholar 

  50. Sostman HD, Matthay RA, Putman CE. Cytotoxic drug-induced lung disease. Am J Med 1977; 62: 608–614.

    Article  PubMed  CAS  Google Scholar 

  51. Demeter SL, Ahmad M, Tomashefski JF. Drug-induced pulmonary disease. Cleve Clin Q 1979; 46: 89–124.

    PubMed  CAS  Google Scholar 

  52. Weiss RB, Muggia FM. Cytotoxic drug-induced pulmonary disease: Update 1980. Am J Med 1980; 68: 259266.

    Google Scholar 

  53. Cooper JAD Jr, White DA, Matthay RA. Drug-induced pulmonary disease. Am Rev Respir Dis 1986; 133: 321340, 488–505.

    PubMed  CAS  Google Scholar 

  54. Jennings FL, Arden A. Development of radiation pneumonitis: time and dose factors. Arch Pathol Lab Med 1962; 74: 351–360.

    Google Scholar 

  55. Gross NJ. Pulmonary effect of radiation therapy. Ann Intern Med 1977; 86: 81–92.

    Article  PubMed  CAS  Google Scholar 

  56. Williams DM, Krick JA, Remington JS. Pulmonary infection in the compromised host. Am Rev Respir Dis 1976;114: 359–394, 593–627.

    Google Scholar 

  57. Levin DC, Wicks AB, Ellis JH, Jr. Transbronchial lung biopsy via the fiberoptic bronchoscope. Am Rev Respir Dis 1974; 110: 4–12.

    PubMed  CAS  Google Scholar 

  58. Ellis JH. Transbronchial lung biopsy via the fiberoptic bronchoscope. Experience with 107 consecutive cases and comparison with bronchial brushing. Chest 1975; 68: 524–532.

    Article  PubMed  Google Scholar 

  59. Hanson RR, Zavala DC, Rhodes ML, Keim LW. Trans-bronchial biopsy via flexible fiberoptic bronchoscope: Results in 164 patients. Am Rev Respir Dis 1976; 114: 67–72.

    PubMed  CAS  Google Scholar 

  60. Matthay RA, Farmer WC, Odero D. Diagnostic fiberoptic bronchoscopy in the immunosuppressed host with pulmonary infiltrates. Thorax 1977; 32: 539–545.

    Article  PubMed  CAS  Google Scholar 

  61. Cunningham JH, Zavala DC, Corry RJ, Keim LW. Trephine air drill, bronchial brush and fiberoptic trans-bronchial lung biopsies in immunosuppressed patients. Am Rev Respir Dis 1977; 115: 213–220.

    PubMed  CAS  Google Scholar 

  62. Feldman NT, Pennington JE, Ehrie MG. Transbronchial lung biopsy in the compromised host. JAMA 1977; 283: 1377–1379.

    Article  Google Scholar 

  63. Lauver GL, Hasan FM, Morgan RB, Campbell SC. The usefulness of fiberoptic bronchoscopy in evaluating new pulmonary lesions in the compromised host. Am J Med 1979; 66: 580–585.

    Article  PubMed  CAS  Google Scholar 

  64. Poe RH, Utell MJ, Israel RH, Hall WJ, Eshleman JD. Sensitivity and specificity of the nonspecific transbronchial lung biopsy. Am Rev Respir Dis 1979; 119: 25–31.

    PubMed  CAS  Google Scholar 

  65. Phillips MJ, Knight RK, Green M. Fiberoptic bronchoscopy and diagnosis of pulmonary lesions in lymphoma and leukemia. Thorax 1980; 35: 19–25.

    Article  PubMed  CAS  Google Scholar 

  66. Chopra SK, Mohsenifar Z. Fiberoptic bronchoscopy in diagnosis of opportunistic infections-assessment of sputa, washings, brushings and biopsy specimens. West J Med 1979; 131: 4–7.

    PubMed  CAS  Google Scholar 

  67. Katzenstein A-L A, Askin FB. Interpretation and significance of pathologic findings in transbronchial lung biopsy. Am J Surg Pathol 1980; 4: 223–234.

    Article  PubMed  CAS  Google Scholar 

  68. Puska S, Hutcheon MA, Hyland RH. Usefulness of transbronchial biopsy in immunosuppressed patients with pulmonary infiltrates. Thorax 1983; 38: 146–250.

    Article  Google Scholar 

  69. Williams B, Yungbluth M, Adams G, Glassroth J. The role of fiberoptic bronchoscopy in the evaluation of the immunocompromised hosts with diffuse pulmonary infiltrates. Am Rev Respir Dis 1985; 131: 880–885.

    PubMed  CAS  Google Scholar 

  70. Fechner RE, Greenberg SD, Wilson RK, Stevens PM. Evaluation of transbronchial biopsy of the lung. Am J Clin Pathol 1977; 68: 17–20.

    PubMed  CAS  Google Scholar 

  71. Roback SA, Weintraub WH, Nesbit M, Spanos PK, Burke B, Leonard AS. Diagnostic open lung biopsy in the critically ill child. Pediatrics 1973; 52: 605–608.

    PubMed  CAS  Google Scholar 

  72. Rosen PP, Martini N, Armstrong D. Pneumocystis carinii pneumonia: Diagnosis by lung biopsy. Am J Med 1975; 58: 794–802.

    Article  PubMed  CAS  Google Scholar 

  73. Nelems JM, Cooper JD, Henderson RD, Peng T, Phillips MJ. Emergency open lung biopsy. Ann Thorac Surg 1976; 22: 260–263.

    Article  PubMed  CAS  Google Scholar 

  74. Pennington JE, Feldman NT. Pulmonary infiltrates and fever in patients with hematologic malignancy: Assessment of transbronchial biopsy. Am J Med 1977; 62: 58 1587.

    Google Scholar 

  75. Wolff LJ, Bartlett M, Baehner RL, Grosfeld JL, Smith JW. The causes of interstitial pneumonia in immunocompromised children. An aggressive systemic opproach to diagnosis. Pediatrics 1977; 60: 41–45.

    PubMed  CAS  Google Scholar 

  76. Leight GS Jr, Michaelis LL. Open lung biopsy for the diagnosis of acute, diffuse pulmonary infiltrates in the immunosuppressed patient. Chest 1978; 73: 477–482.

    Article  PubMed  Google Scholar 

  77. Singer C, Armstrong D, Rosen PP, Walzer PD, Yu B. Diffuse pulmonary infiltrates immunosuppressed patients: Prospective study of 80 cases. Am J Med 1979; 66: 110–120.

    Article  PubMed  CAS  Google Scholar 

  78. Rossiter SJ, Miller C, Churg AM, Carrington CB, Mark JBD. Open lung biopsy in the immunosuppressed patient: Is it really beneficial? J Thorac Cardiovasc Surg 1979; 77: 338–345.

    PubMed  CAS  Google Scholar 

  79. Toledo-Pereyra LH, DeMeester TR, Kinealey A, Mac-Mahon H, Churg A, Golomb H. The benefits of open lung biopsy in patients with previous nondiagnostic transbronchial lung biopsy: A guide to appropriate therapy. Chest 1980; 77: 647–650.

    Article  PubMed  CAS  Google Scholar 

  80. Tenholder MF, Hooper RG. Pulmonary infiltrates in leukemia. Chest 1980; 78: 468–473.

    Article  PubMed  CAS  Google Scholar 

  81. Waltzer WC, Sterioff S, Zincke H, Bernetz PE, Brewer NS. Open lung biopsy in the renal transplant recipient. Surgery 1980; 88: 601–610.

    PubMed  CAS  Google Scholar 

  82. Canham EM, Kennedy TC, Merrick TA. Unexplained pulmonary infiltrates in the compromised patient: An invasive investigation in a consecutive series. Cancer (Philadelphia) 1983; 52: 325–329.

    Article  CAS  Google Scholar 

  83. McKenna RJ, Jr, Mountain CF, McMurtry MJ. Open lung biopsy in immunocompromised patients. Chest 1984; 86: 671–674.

    Article  PubMed  Google Scholar 

  84. Prober CG, Whyte H, Smith CR. Open lung biopsy in immunocompromised children with pulmonary infiltrates. Am J Dis Child 1984; 138: 60–63.

    PubMed  CAS  Google Scholar 

  85. Cockerill FR, III, Wilson WR, Carpenter HA, Smith TF, Rosenow EC, III. Open lung biopsy in immunocompromised patients. Arch Intern Med 1985; 145: 1398–1404.

    Article  PubMed  Google Scholar 

  86. Neff TA. Lung biopsy: How vs. whom? Chest 1976; 70: 201–202.

    Article  CAS  Google Scholar 

  87. Webster J, Clarke J. A doctor’s dilemma-1980. Chest 1980; 78: 417–418.

    Article  PubMed  CAS  Google Scholar 

  88. Wardman AG, Cooke NJ. Pulmonary infiltrates in adult acute leukemia: Empirical treatment or lung biopsy. Thorax 1984; 35: 647–650.

    Article  Google Scholar 

  89. Reuben DB. Learning diagnostic restraint. N Engl J Med 1984; 310: 591–595.

    Article  PubMed  CAS  Google Scholar 

  90. Robin ED, Burke CM. Lung biopsy in immunosuppressed patients. Chest 1986; 89: 276–278.

    Article  PubMed  CAS  Google Scholar 

  91. Wilson RK, Fechner RE, Greenberg SD, Estrada R, Stevens PM. Clinical implications of a nonspecific trans-bronchial biopsy. Am J Med 1978; 65: 252–256.

    Article  PubMed  CAS  Google Scholar 

  92. Ray JF, III, Lawton BR, Myers WO, et al. Open pulmonary biopsy: 19 years experience with 416 consecutive operations. Chest 1976; 69: 43–47.

    Article  PubMed  Google Scholar 

  93. Wall CP, Gaensler EA, Carrington CB, Hayes JA. Comparison of transbronchial and open lung biopsies in chronic infiltrative-lung diseases. Am Rev Respir Dis 1981; 123: 280–285.

    PubMed  CAS  Google Scholar 

  94. Buechner HA. Differential diagnosis of miliary diseases of lung. Med Clin North Am 1959; 43: 89–112.

    PubMed  CAS  Google Scholar 

  95. Epler GR, McLoud TC, Gaensler EA, Mikus JP, Car rington CB. Normal chest roentgenograms in chronic diffuse infiltrative lung disease. N Engl J Med 1978; 298: 934–939.

    Article  PubMed  CAS  Google Scholar 

  96. Scadding JG. Lung biopsy in the diagnosis of diffuse lung disease. Br Med J 1970; 2: 557–564.

    Article  PubMed  CAS  Google Scholar 

  97. Zavala DC. Diagnostic fiberoptic bronchoscopy: Techniques and results of biopsy in 600 patients. Chest 1975; 68: 12–19.

    Article  PubMed  CAS  Google Scholar 

  98. Koerner SK, Sakowitz AJ, Appelman RI, et al. Trans-bronchial lung biopsy for the diagnosis of sarcoidosis. N Engl J Med 1975; 293: 268–270.

    Article  PubMed  CAS  Google Scholar 

  99. Poe RH, Israel RH, Utell MJ, Hall WJ. Probability of a positive transbronchial lung biopsy result in sarcoidosis. Arch Intern Med 1979; 139: 761–763.

    Article  PubMed  CAS  Google Scholar 

  100. Koontz CH, Joyner LR, Nelson RA. Transbronchial lung biopsy via the fiberoptic bronchoscope in sarcoidosis. Ann Intern Med 1976; 85: 64–66.

    Article  Google Scholar 

  101. Joyner LR, Schneinhorn DJ. Transbronchial forceps lung biopsy through the fiberoptic bronchoscope. Chest 1975; 67: 532–535.

    Article  PubMed  CAS  Google Scholar 

  102. Smith CW, Murray GF, Wilcox BR. The role of trans-bronchial lung biopsy in diffuse pulmonary disease. Ann Thorac Surg 1977; 24: 54–58.

    Article  PubMed  CAS  Google Scholar 

  103. ILO U/C. 1971 International classification of radiographs of the pneumoconioses. Med Radiogr Photogr 1972; 48: 67–76.

    Google Scholar 

  104. International Labour Office: Guidelines for the Use of ILO International Classification of Radiographs of Pneumoconioses. Geneva: International Labour Office, 1980.

    Google Scholar 

  105. McLoud TC, Gaensler EA, Carrington CB. Chronic diffuse infiltrative lung disease: Newer approaches. Clin Chest Med 1984; 5: 329–344.

    PubMed  CAS  Google Scholar 

  106. Lemberskaya EY. Morphological changes in the areas of the lingual segment of the lung, biopsied during mitral commissurotomy. Arkh Patol 1967; 29: 20–23.

    Google Scholar 

  107. Vogt T, Fauser A, Schlosser V, et al. Patho-histological findings in lung biopsies in patients following mitral commissurotomy and morphometric examination of the upper and lower lobes of the lung. Bull Soc Int Chir 1975; 34: 147–151.

    PubMed  CAS  Google Scholar 

  108. Newman SL, Michel RP, Wang NS. Lingular lung biopsy: Is it representative? Am Rev Respir Dis 1985; 132: 1084–1086.

    PubMed  CAS  Google Scholar 

  109. Wetstein L. Sensitivity and specificity of lingular segmental biopsies of the lung. Chest 1986; 90: 383–386.

    Article  PubMed  CAS  Google Scholar 

  110. Miller RR, Nelems B, Muller NL, et al. Lingular and right middle lobe biopsy in the assessment of diffuse lung disease. Ann Thorac Surg 1987; 44: 269–272.

    Article  PubMed  CAS  Google Scholar 

  111. Klassen KP, Andrews NC. Biopsy of diffuse pulmonary lesions: a seventeen-year experience. Ann Thorac Surg 1967; 4: 117–124.

    Article  PubMed  CAS  Google Scholar 

  112. Ulbright TM, Katzenstein A-L A. Solitary necrotizing granulomas of the lung: Differentiating features and etiology. Am J Surg Pathol 1980; 4: 13–28.

    PubMed  CAS  Google Scholar 

  113. Askin FB, Katzenstein AA. Pneumocystis infection masquerading as diffuse alveolar damage: a potential source of diagnostic error. Chest 1981; 79: 420–422.

    Article  PubMed  CAS  Google Scholar 

  114. Narat JK, Loef JA, Narat M. On the preparation of multicolored corrosion specimens. Anat Rec 1936; 64: 155–160.

    Article  Google Scholar 

  115. Tompsett DH. Anatomical techniques. 2d Ed. Edinburgh: Livingstone, 1970.

    Google Scholar 

  116. Heard BE. A pathological study of emphysema of the lungs with chronic bronchitis. Thorax 1958; 13: 136149.

    Google Scholar 

  117. Pratt PC. Preparation of normal and emphysematous lung tissue for structural study of bronchioles, alveolar ducts, and alveoli. Am Rev Tuberc 1959; 79: 842–843.

    Google Scholar 

  118. Heard BE. Pathology of pulmonary emphysema: methods of study. Am Rev Respir Dis 196Q; 82: 792–799.

    Google Scholar 

  119. Heard BE, Esterly JR, Wootliff JS. A modified apparatus for fixing lungs to study the pathology of emphysema. Am Rev Respir Dis 1967; 95: 311–312.

    PubMed  CAS  Google Scholar 

  120. Sils B. A multidisciplinary method for study of lung structure and function. Am Rev Respir Dis 1962; 86: 238–245.

    Google Scholar 

  121. Markarian B. A simple method of inflation-fixation and air-drying of lungs. Am J Clin Pathol 1975; 63: 20–24.

    PubMed  CAS  Google Scholar 

  122. Heitzman ER. The lung: radiologic-pathologic correlations. 2d Ed. St. Louis: Mosby, 1984.

    Google Scholar 

  123. Pratt PC, Klugh ‘GA. A technique for the study of ventilatory capacity, compliance, and residual volume of excised lungs and for fixation, drying, and serial sectioning in the inflated state. Am Rev Respir Dis 1961; 83: 690–696.

    PubMed  CAS  Google Scholar 

  124. Gough J, Wentworth JE. The use of thin sections of entire organs in morbid anatomical studies. J R Microsc Soc 1949; 69: 231–235.

    Article  Google Scholar 

  125. Gough J. Diseases of the lung. In: Harrison CV, ed. Recent advances in pathology. Vol 7. London: Churchill, 1960: 54–86.

    Google Scholar 

  126. Whimster WF. Rapid giant paper sections of lungs. Thorax 1969; 24: 737–741.

    Article  PubMed  CAS  Google Scholar 

  127. Whimster WF. Techniques for the examination of excised lungs. Hum Pathol 1970; 1: 305–314.

    Article  PubMed  CAS  Google Scholar 

  128. Timbrell V, Bevan NE, Davies AS, Munday DE. Hollow casts of lungs for experimental purposes. Nature (London) 1970; 225: 97–98.

    Article  CAS  Google Scholar 

  129. Eisman MM. Lung models: hollow, flexible reproductions. J Appl Physiol 1970; 29: 531–533.

    PubMed  CAS  Google Scholar 

  130. Kilpper RW, Stidd PJ. A wet lung technique for obtaining silastic rubber casts of the respiratory airways. Anat Rec 1973; 176: 279–288.

    Article  PubMed  CAS  Google Scholar 

  131. Wang NS, Ying WC. A scanning electron microscopic study of alkali-digested human and rabbit alveoli. Am Rev Respir Dis 1977; 115: 449–460.

    PubMed  CAS  Google Scholar 

  132. Lauweryns JM. The blood and lymphatic microcirculation of the lung. Pathol Annu 1971; 6: 365–415.

    PubMed  CAS  Google Scholar 

  133. Liebow AA, Hales MR, Lindskog GE, Bloomer WE. Plastic demonstrations of pulmonary pathology. Bull Int Assoc Med Museums 1947; 27: 116–129.

    Google Scholar 

  134. Moolten SE. A simple apparatus for fixation of lungs in the inflated state. Arch Pathol Lab Med 1935; 20: 77–80.

    Google Scholar 

  135. Hales MR, Carrington CB. A pigmented gelatin mass for vascular injection. Yale J Biol Med 1971; 43: 257–270.

    PubMed  CAS  Google Scholar 

  136. Schlesinger MJ. New radiopaque mass for vascular injection. Lab Invest 1957; 6: 1–11.

    PubMed  CAS  Google Scholar 

  137. Reynolds DG. Injection techniques in the study of intestinal vasculature under normal conditions and in ulcerative colitis. In: Boley SC, ed. Vascular disorders of the intestine. New York: Appleton-Century-Crofts, 1971: 383–395.

    Google Scholar 

  138. Mitsudo SM, Boley SJ, Brandt LJ, Montefusco CM, Sammartano RJ. Vascular ectasias of the right colon in the elderly: A distinct pathologic entity. Hum Pathol 1979; 10: 585–600.

    Article  PubMed  CAS  Google Scholar 

  139. Case records of the Massachusetts General Hospital. Case 36–1974. N Engl J Med 1974; 291: 569–575.

    Google Scholar 

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Dail, D.H. (1994). Tissue Sampling. In: Dail, D.H., Hammar, S.P. (eds) Pulmonary Pathology. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-3935-0_1

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